Tan Lab | DSigDB

Gene Set: D4 : CTD - lycopene

Collection

D4 : CTD

Chemical Name

lycopene ( From PubChem : SPECTRUM_001666 )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
536.873 g/mol	0	0	12.938	False(2/4)

Structure

InChI

InChI=1S/C40H56/c1-33(2)19-13-23-37(7)27-17-31-39(9)29-15-25-35(5)21-11-12-22-36(6)26-16-30-40(10)32-18-28-38(8)24-14-20-34(3)4/h11-12,15-22,25-32H,13-14,23-24H2,1-10H3

InChIKey

OAIJSZIZWZSQBC-UHFFFAOYSA-N

Links

Gene (86 / 124)

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Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(expression)			ADD1		C015329
CTD	decreases(reaction)			AGER		C015329
CTD	increases(expression)			AGER		C015329
CTD	decreases(expression)			AHR		C015329
CTD	decreases(phosphorylation)			AKT1		C015329
CTD	decreases(expression)			AR		C015329
CTD	increases(expression)			BACH1		C015329
CTD	increases(expression)			BAP1		C015329
CTD	decreases(expression)			BRAF		C015329
CTD	decreases(expression)			CASP8		C015329
CTD	increases(expression)			CAT		C015329
CTD	decreases(reaction)			CCND1		C015329
CTD	increases(expression)			CCND1		C015329
CTD	decreases(reaction)			CCND1		C015329
CTD	increases(expression)			CCND1		C015329
CTD	decreases(expression)			CCND1		C015329
CTD	decreases(expression)			CCNE1		C015329
CTD	increases(expression)			CCNE1		C015329
CTD	decreases(expression)			CDK1		C015329
CTD	decreases(expression)			CDK4		C015329
CTD	decreases(expression)			CDK5		C015329
CTD	decreases(expression)			CDK7		C015329
CTD	decreases(expression)			CDK9		C015329
CTD	decreases(reaction)			CDKN1A		C015329
CTD	increases(expression)			CDKN1A		C015329
CTD	increases(expression)			CHGA		C015329
CTD	decreases(expression)			CHGB		C015329
CTD	decreases(expression)			CRB1		C015329
CTD	increases(activity)			CYP3A4		C015329
CTD	increases(expression)			DDB2		C015329
CTD	increases(expression)			EIF4G1		C015329
CTD	decreases(reaction)			ESR1		C015329
CTD	increases(activity)			ESR1		C015329
CTD	increases(expression)			ESR1		C015329
CTD	decreases(reaction)			ESR2		C015329
CTD	increases(activity)			ESR2		C015329
CTD	decreases(expression)			FANCC		C015329
CTD	decreases(expression)			FANCF		C015329
CTD	decreases(expression)			FASLG		C015329
CTD	increases(expression)			FOS		C015329
CTD	decreases(expression)			GJA4		C015329
CTD	decreases(expression)			GJA5		C015329
CTD	increases(expression)			GJA5		C015329
CTD	decreases(expression)			GPX4		C015329
CTD	decreases(reaction)			HMGB1		C015329
CTD	increases(expression)			HMGB1		C015329
CTD	increases(secretion)			HMGB1		C015329
CTD	decreases(response to substance)			HMGB1		C015329
CTD	decreases(reaction)			ICAM1		C015329
CTD	increases(expression)			ICAM1		C015329
CTD	decreases(reaction)			IGF1		C015329
CTD	increases(expression)			IGF1		C015329
CTD	increases(phosphorylation)			IGF1		C015329
CTD	decreases(expression)			IGF1		C015329
CTD	increases(expression)			IGF1		C015329
CTD	decreases(expression)			IGF1R		C015329
CTD	increases(expression)			IGFBP2		C015329
CTD	decreases(expression)			IVL		C015329
CTD	increases(expression)			JAK1		C015329
CTD	decreases(expression)			JUN		C015329
CTD	increases(expression)			KIF2A		C015329
CTD	increases(expression)			KPNA2		C015329
CTD	increases(expression)			LDLR		C015329
CTD	increases(expression)			LIPA		C015329
CTD	increases(expression)			MAP2K1		C015329
CTD	decreases(expression)			MAP2K2		C015329
CTD	decreases(expression)			MAP2K4		C015329
CTD	decreases(expression)			MAP2K6		C015329
CTD	decreases(expression)			MAPK14		C015329
CTD	increases(expression)			MAPK14		C015329
CTD	decreases(expression)			MAPK3		C015329
CTD	decreases(expression)			MAPK8		C015329
CTD	increases(expression)			MGAT2		C015329
CTD	increases(expression)			MICA		C015329
CTD	increases(expression)			MLH1		C015329
CTD	increases(expression)			MSH2		C015329
CTD	increases(expression)			MSH6		C015329
CTD	decreases(expression)			NOS1		C015329
CTD	decreases(expression)			NUP214		C015329
CTD	decreases(reaction)			PLA2G2A		C015329
CTD	increases(expression)			PLA2G2A		C015329
CTD	increases(secretion)			PLA2G2A		C015329
CTD	decreases(expression)			PRKDC		C015329
CTD	increases(expression)			RAD50		C015329
CTD	increases(expression)			RASSF7		C015329
CTD	decreases(activity)			RB1		C015329
CTD	decreases(reaction)			RB1		C015329
CTD	increases(phosphorylation)			RB1		C015329
CTD	decreases(reaction)			RB1		C015329
CTD	increases(phosphorylation)			RB1		C015329
CTD	decreases(phosphorylation)			RB1		C015329
CTD	decreases(expression)			RDX		C015329
CTD	decreases(expression)			RPS6KA1		C015329
CTD	decreases(expression)			RPS6KA3		C015329
CTD	increases(expression)			RRM2		C015329
CTD	decreases(reaction)			SELE		C015329
CTD	increases(expression)			SELE		C015329
CTD	decreases(expression)			SEPP1		C015329
CTD	increases(expression)			SMAD3		C015329
CTD	decreases(expression)			SMC1A		C015329
CTD	increases(expression)			STAT3		C015329
CTD	decreases(expression)			TFF1		C015329
CTD	decreases(expression)			TFPI2		C015329
CTD	increases(expression)			TGFA		C015329
CTD	decreases(reaction)			TLR2		C015329
CTD	increases(expression)			TLR2		C015329
CTD	decreases(reaction)			TLR4		C015329
CTD	increases(expression)			TLR4		C015329
CTD	decreases(reaction)			TNF		C015329
CTD	increases(expression)			TNF		C015329
CTD	increases(secretion)			TNF		C015329
CTD	decreases(expression)			TP53		C015329
CTD	decreases(reaction)			VCAM1		C015329
CTD	increases(expression)			VCAM1		C015329
CTD	increases(expression)			VCP		C015329
CTD	decreases(expression)			WRB		C015329
CTD	increases(expression)			ZNF138		C015329
PubChem	Ratio Potency (uM)	uM	19.739	AR	-	GI(Protien) :
PubChem	Potency	uM	19.953	EHMT2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	6.682	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	7.562	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	13.960	ESR1	-	GI(Protien) :
PubChem	Potency	uM	18.837	GMNN	-	GI(Protien) :
ChEMBL	Potency	nM	19952.600	EHMT2	-	Target : CHEMBL6032

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