Tan Lab | DSigDB

Gene Set: D4 : CTD - Aspartame

Collection

D4 : CTD

Chemical Name

Aspartame ( From PubChem : ASPARTAME )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
294.303 g/mol	3	7	0.7801	True

Structure

InChI

InChI=1S/C14H18N2O5/c1-21-14(20)11(7-9-5-3-2-4-6-9)16-13(19)10(15)8-12(17)18/h2-6,10-11H,7-8,15H2,1H3,(H,16,19)(H,17,18)/t10-,11-/m0/s1

InChIKey

Links

Gene (14 / 23)

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Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(activity)			ACHE		D001218
CTD	decreases(activity)			F2		D001218
CTD	increases(secretion)			IL6		D001218
CTD	increases(expression)			INS		D001218
CTD	increases(secretion)			KDR		D001218
CTD	increases(phosphorylation)			MAPK1		D001218
CTD	increases(phosphorylation)			MAPK3		D001218
CTD	increases(expression)			POMC		D001218
CTD	decreases(activity)			SLC15A1		D001218
CTD	affects(binding)			TAS1R2		D001218
CTD	increases(activity)			TAS1R2		D001218
CTD	affects(binding)			TAS1R2		D001218
CTD	affects(binding)			TAS1R2		D001218
CTD	affects(binding)			TAS1R2		D001218
CTD	decreases(reaction)			TAS1R2		D001218
CTD	increases(activity)			TAS1R2		D001218
CTD	affects(binding)			TAS1R3		D001218
CTD	affects(binding)			TAS1R3		D001218
CTD	decreases(reaction)			TAS1R3		D001218
CTD	increases(activity)			TAS1R3		D001218
CTD	increases(activity)			TRPV1		D001218
CTD	increases(secretion)			VEGFA		D001218
PubChem	AhR Potency (uM)	uM	10.591	AHR	-	GI(Protien) :

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