Drug Gene Type Source aspartame ACHE Text_Mining(decreases(activity)) CTD aspartame F2 Text_Mining(decreases(activity)) CTD aspartame IL6 Text_Mining(increases(secretion)) CTD aspartame INS Text_Mining(increases(expression)) CTD aspartame KDR Text_Mining(increases(secretion)) CTD aspartame MAPK1 Text_Mining(increases(phosphorylation)) CTD aspartame MAPK3 Text_Mining(increases(phosphorylation)) CTD aspartame POMC Text_Mining(increases(expression)) CTD aspartame SLC15A1 Text_Mining(decreases(activity)) CTD aspartame TAS1R2 Text_Mining(affects(binding)) CTD aspartame TAS1R2 Text_Mining(increases(activity)) CTD aspartame TAS1R2 Text_Mining(decreases(reaction)) CTD aspartame TAS1R3 Text_Mining(affects(binding)) CTD aspartame TAS1R3 Text_Mining(decreases(reaction)) CTD aspartame TAS1R3 Text_Mining(increases(activity)) CTD aspartame TRPV1 Text_Mining(increases(activity)) CTD aspartame VEGFA Text_Mining(increases(secretion)) CTD aspartame AHR AhR Potency (uM)=10.5909(uM) D4 PubChem