Tan Lab | DSigDB

Gene Set: D4 : CTD - alsterpaullone

Collection

D4 : CTD

Chemical Name

alsterpaullone ( From PubChem : ALSTERPAULLONE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
293.277 g/mol	2	2	3.8989	True

Structure

InChI

InChI=1S/C16H11N3O3/c20-15-8-12-11-7-9(19(21)22)5-6-14(11)18-16(12)10-3-1-2-4-13(10)17-15/h1-7,18H,8H2,(H,17,20)

InChIKey

Links

Gene (19 / 29)

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Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(activity)			AR		C120793
CTD	decreases(activity)			CDK2		C120793
CTD	decreases(activity)			GSK3B		C120793
CTD	increases(expression)			KLK3		C120793
CTD	decreases(activity)			LCK		C120793
CTD	affects(localization)			TP53		C120793
CTD	decreases(degradation)			TP53		C120793
CTD	increases(expression)			TP53		C120793
PubChem	None	uM		CFTR	-	GI(Protien) :
PubChem	None	uM		IL1B	-	GI(Protien) :
PubChem	None	uM		NCOA2	-	GI(Protien) :
PubChem	None	uM		NCOA3	-	GI(Protien) :
PubChem	None	uM		NCOA3	-	GI(Protien) :
PubChem	Potency	uM	2.311	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	2.311	NFE2L2	-	GI(Protien) :
PubChem	None	uM		NR2E3	-	GI(Protien) :
PubChem	None	uM		NR2E3	-	GI(Protien) :
PubChem	None	uM		NR2F2	-	GI(Protien) :
PubChem	None	uM		OPRD1	-	GI(Protien) :
PubChem	None	uM		OPRM1	-	GI(Protien) :
PubChem	Potency	uM	0.164	SMAD3	-	GI(Protien) :
PubChem	Potency	uM	0.501	SMAD3	-	GI(Protien) :
PubChem	Potency	uM	1.300	SMAD3	-	GI(Protien) :
PubChem	None	uM		SMARCA2	-	GI(Protien) :
PubChem	None	uM		SMARCA2	-	GI(Protien) :
PubChem	None	uM		STK33	-	GI(Protien) :
PubChem	Potency	uM	1.836	TDP1	-	GI(Protien) :
PubChem	Potency	uM	1.836	TDP1	-	GI(Protien) :
ChEMBL	Potency	nM	2310.900	NFE2L2	-	Target : CHEMBL1075094

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