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Gene Set: D4 : CTD - sitaxsentan

Collection D4 : CTD
Chemical Name sitaxsentan ( From PubChem : SITAXENTAN )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotApprovedNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
454.905 g/mol 1 9 5.115 False(3/4)
Structure
InChI InChI=1S/C18H15ClN2O6S2/c1-9-5-13-14(26-8-25-13)7-11(9)6-12(22)17-15(3-4-28-17)29(23,24)21-18-16(19)10(2)20-27-18/h3-5,7,21H,6,8H2,1-2H3
InChIKey PHWXUGHIIBDVKD-UHFFFAOYSA-N
Links

Gene (9 / 15)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
CTDdecreases(activity)ABCB11
C106276
CTDdecreases(reaction)CYP2C19
C106276
CTDincreases(metabolic processing)CYP2C19
C106276
CTDdecreases(reaction)CYP2C8
C106276
CTDincreases(metabolic processing)CYP2C8
C106276
CTDdecreases(reaction)CYP2C9
C106276
CTDincreases(metabolic processing)CYP2C9
C106276
CTDdecreases(activity)CYP3A4
C106276
CTDaffects(binding)EDNRA
C106276
CTDdecreases(activity)EDNRA
C106276
CTDdecreases(reaction)FN1
C106276
CTDincreases(expression)FN1
C106276
CTDdecreases(reaction)RELA
C106276
CTDincreases(activity)RELA
C106276
PubChem NoneuMPPARG-GI(Protien) :
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