Tan Lab | DSigDB

Gene Set: D4 : CTD - Am 580

Collection

D4 : CTD

Chemical Name

Am 580 ( From PubChem : AM580 )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
351.439 g/mol	2	4	5.0591	False(3/4)

Structure

InChI

InChI=1S/C22H25NO3/c1-21(2)11-12-22(3,4)18-13-15(7-10-17(18)21)19(24)23-16-8-5-14(6-9-16)20(25)26/h5-10,13H,11-12H2,1-4H3,(H,23,24)(H,25,26)

InChIKey

SZWKGOZKRMMLAJ-UHFFFAOYSA-N

Links

Gene (115 / 142)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(expression)			ABCG2		C068073
CTD	increases(reaction)			ABCG2		C068073
CTD	increases(expression)			ADA		C068073
CTD	increases(expression)			AGPAT4		C068073
CTD	decreases(expression)			AGRN		C068073
CTD	increases(expression)			AJAP1		C068073
CTD	increases(expression)			APLP2		C068073
CTD	decreases(expression)			ATP2B1		C068073
CTD	increases(expression)			BAG2		C068073
CTD	decreases(expression)			C16ORF46		C068073
CTD	decreases(expression)			C4ORF32		C068073
CTD	decreases(expression)			CALCRL		C068073
CTD	decreases(expression)			CD1A		C068073
CTD	increases(expression)			CD1D		C068073
CTD	decreases(reaction)			CD1D		C068073
CTD	increases(expression)			CD1D		C068073
CTD	increases(expression)			CD300A		C068073
CTD	increases(expression)			CD300LB		C068073
CTD	increases(expression)			CD300LF		C068073
CTD	decreases(reaction)			CD38		C068073
CTD	increases(expression)			CD38		C068073
CTD	affects(cotreatment)			CD38		C068073
CTD	affects(localization)			CDKN1B		C068073
CTD	decreases(expression)			CDR2L		C068073
CTD	increases(expression)			CGB		C068073
CTD	increases(expression)			COL5A3		C068073
CTD	decreases(expression)			CTTNBP2		C068073
CTD	increases(expression)			CYP19A1		C068073
CTD	increases(expression)			DCSTAMP		C068073
CTD	increases(expression)			DHRS3		C068073
CTD	decreases(expression)			DMPK		C068073
CTD	decreases(expression)			DMWD		C068073
CTD	increases(expression)			DNAJC5B		C068073
CTD	increases(expression)			ETS2		C068073
CTD	increases(expression)			FAM101B		C068073
CTD	decreases(expression)			FAM109A		C068073
CTD	increases(expression)			FN1		C068073
CTD	decreases(expression)			FUT7		C068073
CTD	increases(expression)			GALM		C068073
CTD	increases(expression)			GDF15		C068073
CTD	decreases(expression)			GOLGA8A		C068073
CTD	decreases(expression)			GPD1L		C068073
CTD	increases(expression)			GUSB		C068073
CTD	increases(expression)			HIPK2		C068073
CTD	decreases(expression)			HIST1H2BD		C068073
CTD	decreases(expression)			HLX		C068073
CTD	increases(expression)			IFNGR1		C068073
CTD	decreases(reaction)			IFNGR1		C068073
CTD	decreases(expression)			IL1R1		C068073
CTD	decreases(expression)			IL1RAP		C068073
CTD	increases(expression)			INPP5F		C068073
CTD	decreases(expression)			IPCEF1		C068073
CTD	affects(localization)			IRF1		C068073
CTD	increases(expression)			IRF1		C068073
CTD	increases(activity)			IRF1		C068073
CTD	increases(expression)			IRF1		C068073
CTD	decreases(reaction)			IRF1		C068073
CTD	increases(reaction)			IRF1		C068073
CTD	increases(expression)			ITGAE		C068073
CTD	decreases(expression)			KIAA0040		C068073
CTD	decreases(expression)			KIAA1161		C068073
CTD	decreases(expression)			KIFC2		C068073
CTD	increases(expression)			LAIR1		C068073
CTD	decreases(expression)			LELP1		C068073
CTD	increases(expression)			LILRA1		C068073
CTD	decreases(expression)			LRP11		C068073
CTD	decreases(expression)			MAN1C1		C068073
CTD	decreases(expression)			MAP3K6		C068073
CTD	decreases(expression)			MAP4K1		C068073
CTD	affects(cotreatment)			MAPK1		C068073
CTD	increases(activity)			MAPK1		C068073
CTD	increases(phosphorylation)			MAPK1		C068073
CTD	affects(cotreatment)			MAPK3		C068073
CTD	increases(activity)			MAPK3		C068073
CTD	increases(phosphorylation)			MAPK3		C068073
CTD	decreases(expression)			METRN		C068073
CTD	decreases(expression)			MGAT4C		C068073
CTD	decreases(expression)			NDRG2		C068073
CTD	increases(expression)			NRIP1		C068073
CTD	increases(expression)			NRIP3		C068073
CTD	decreases(expression)			NUDT7		C068073
CTD	increases(expression)			OAS2		C068073
CTD	decreases(reaction)			OAS2		C068073
CTD	increases(expression)			OCLN		C068073
CTD	increases(expression)			OLR1		C068073
CTD	increases(expression)			OMA1		C068073
CTD	decreases(expression)			PALD1		C068073
CTD	increases(expression)			PAPSS2		C068073
CTD	decreases(expression)			PDLIM2		C068073
CTD	decreases(expression)			PDLIM4		C068073
CTD	decreases(expression)			PHLDA2		C068073
CTD	increases(expression)			PLBD1		C068073
CTD	decreases(expression)			PON2		C068073
CTD	increases(expression)			PPAP2B		C068073
CTD	increases(expression)			PRAM1		C068073
CTD	decreases(expression)			QPRT		C068073
CTD	decreases(expression)			RAB15		C068073
CTD	increases(expression)			RAB20		C068073
CTD	decreases(expression)			RAP1GAP		C068073
CTD	affects(binding)			RARA		C068073
CTD	increases(activity)			RARA		C068073
CTD	increases(expression)			RARA		C068073
CTD	affects(cotreatment)			RB1		C068073
CTD	decreases(phosphorylation)			RB1		C068073
CTD	increases(expression)			RBP1		C068073
CTD	decreases(expression)			REPS2		C068073
CTD	decreases(expression)			RFXAP		C068073
CTD	increases(expression)			RHOBTB3		C068073
CTD	increases(activity)			RXRA		C068073
CTD	decreases(expression)			SELPLG		C068073
CTD	increases(expression)			SIGLEC17P		C068073
CTD	increases(expression)			SLC26A11		C068073
CTD	increases(expression)			SLITRK4		C068073
CTD	increases(expression)			SNAI3		C068073
CTD	decreases(expression)			SSMEM1		C068073
CTD	increases(activity)			STAT1		C068073
CTD	increases(phosphorylation)			STAT1		C068073
CTD	decreases(reaction)			STAT1		C068073
CTD	increases(activity)			STS		C068073
CTD	decreases(expression)			TACSTD2		C068073
CTD	increases(expression)			TBC1D2		C068073
CTD	decreases(expression)			TBL1X		C068073
CTD	increases(expression)			TBL2		C068073
CTD	affects(cotreatment)			TERT		C068073
CTD	decreases(expression)			TERT		C068073
CTD	affects(cotreatment)			TGM2		C068073
CTD	increases(activity)			TGM2		C068073
CTD	increases(expression)			TGM2		C068073
CTD	increases(expression)			THBS3		C068073
CTD	decreases(expression)			TMEM14A		C068073
CTD	decreases(expression)			TNFSF12		C068073
CTD	decreases(expression)			TNS1		C068073
CTD	decreases(expression)			ZBTB7B		C068073
PubChem	Potency-Replicate_1	uM	48.966	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	48.966	AR	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.004	ESR1	-	GI(Protien) :
PubChem	ER Potency (uM)	uM	0.010	ESR1	-	GI(Protien) :
PubChem	Potency	uM	61.131	NFE2L2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	43.641	NR1H4	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	43.641	NR1H4	-	GI(Protien) :
PubChem	Potency	uM	79.433	VDR	-	GI(Protien) :

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