Tan Lab | DSigDB

Gene Set: D4 : CTD - tripterine

Collection

D4 : CTD

Chemical Name

tripterine ( From PubChem : CELASTROL )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Approved	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
450.61 g/mol	2	4	6.6977	False(3/4)

Structure

InChI

InChI=1S/C29H38O4/c1-17-18-7-8-21-27(4,19(18)15-20(30)23(17)31)12-14-29(6)22-16-26(3,24(32)33)10-9-25(22,2)11-13-28(21,29)5/h7-8,15,22,31H,9-14,16H2,1-6H3,(H,32,33)/t22-,25-,26-,27+,28-,29+/m1/s1

InChIKey

KQJSQWZMSAGSHN-JJWQIEBTSA-N

Links

Gene (102 / 134)

⊖ Less

Source	Type	Unit	Gene	PMID	Other
CTD	increases(expression)		AHSA1		C050414
CTD	increases(expression)		AKR1C1		C050414
CTD	increases(expression)		AKR1C2		C050414
CTD	decreases(phosphorylation)		AKT1		C050414
CTD	decreases(reaction)		AR		C050414
CTD	increases(degradation)		AR		C050414
CTD	decreases(expression)		AR		C050414
CTD	decreases(expression)		ARID5B		C050414
CTD	increases(expression)		ATF3		C050414
CTD	increases(expression)		BAG3		C050414
CTD	increases(expression)		BAX		C050414
CTD	decreases(expression)		BCL2		C050414
CTD	decreases(expression)		BIRC5		C050414
CTD	decreases(expression)		BTG1		C050414
CTD	decreases(expression)		C21ORF33		C050414
CTD	increases(expression)		CACYBP		C050414
CTD	affects(cotreatment)		CASP3		C050414
CTD	increases(cleavage)		CASP3		C050414
CTD	increases(cleavage)		CASP3		C050414
CTD	increases(cleavage)		CASP8		C050414
CTD	increases(cleavage)		CASP9		C050414
CTD	decreases(reaction)		CAST		C050414
CTD	increases(degradation)		CAST		C050414
CTD	increases(expression)		CBR3		C050414
CTD	decreases(expression)		CDC7		C050414
CTD	decreases(expression)		CDK2		C050414
CTD	increases(expression)		CHORDC1		C050414
CTD	decreases(expression)		CITED2		C050414
CTD	decreases(expression)		CYP1A1		C050414
CTD	increases(expression)		DDIT3		C050414
CTD	increases(expression)		DDIT4		C050414
CTD	increases(expression)		DNAJA1		C050414
CTD	increases(expression)		DNAJB4		C050414
CTD	decreases(expression)		EFNB2		C050414
CTD	affects(cotreatment)		EGFR		C050414
CTD	affects(expression)		EGFR		C050414
CTD	decreases(expression)		EGFR		C050414
CTD	decreases(expression)		EGFR		C050414
CTD	increases(expression)		FAS		C050414
CTD	increases(expression)		FASLG		C050414
CTD	increases(expression)		FICD		C050414
CTD	decreases(expression)		FLT3		C050414
CTD	increases(expression)		GCLM		C050414
CTD	increases(expression)		GDF15		C050414
CTD	increases(expression)		GTPBP2		C050414
CTD	decreases(expression)		HILPDA		C050414
CTD	increases(expression)		HMGCS1		C050414
CTD	increases(expression)		HMOX1		C050414
CTD	decreases(activity)		HSP90AA1		C050414
CTD	increases(expression)		HSPA13		C050414
CTD	increases(expression)		HSPA1A		C050414
CTD	increases(expression)		HSPA1B		C050414
CTD	increases(expression)		HSPA5		C050414
CTD	increases(expression)		HSPH1		C050414
CTD	decreases(reaction)		ICAM1		C050414
CTD	increases(expression)		ICAM1		C050414
CTD	decreases(reaction)		IFNG		C050414
CTD	increases(expression)		IFNG		C050414
CTD	decreases(reaction)		IL1B		C050414
CTD	increases(expression)		IL1B		C050414
CTD	decreases(expression)		IL1RN		C050414
CTD	increases(expression)		INSIG1		C050414
CTD	decreases(expression)		JAG1		C050414
CTD	decreases(expression)		KCNN2		C050414
CTD	increases(expression)		LDLR		C050414
CTD	increases(expression)		LPIN1		C050414
CTD	decreases(expression)		LTN1		C050414
CTD	decreases(expression)		MAFB		C050414
CTD	decreases(expression)		MDH2		C050414
CTD	increases(expression)		ME1		C050414
CTD	increases(expression)		MNT		C050414
CTD	increases(expression)		MRPL18		C050414
CTD	decreases(expression)		MSH6		C050414
CTD	increases(expression)		MSMO1		C050414
CTD	decreases(expression)		MYCBP2		C050414
CTD	decreases(expression)		MYNN		C050414
CTD	decreases(expression)		NBN		C050414
CTD	decreases(expression)		NKX3-1		C050414
CTD	decreases(expression)		NREP		C050414
CTD	decreases(expression)		OPRK1		C050414
CTD	increases(expression)		OSER1		C050414
CTD	affects(cotreatment)		PARP1		C050414
CTD	increases(cleavage)		PARP1		C050414
CTD	increases(reaction)		PARP1		C050414
CTD	decreases(expression)		PDE9A		C050414
CTD	decreases(expression)		PIK3CD		C050414
CTD	decreases(expression)		PIK3R1		C050414
CTD	decreases(expression)		PPIF		C050414
CTD	decreases(expression)		PURA		C050414
CTD	affects(localization)		RELA		C050414
CTD	decreases(reaction)		RELA		C050414
CTD	increases(activity)		RELA		C050414
CTD	decreases(expression)		RRM2		C050414
CTD	decreases(reaction)		SELE		C050414
CTD	increases(expression)		SELE		C050414
CTD	increases(expression)		SERP1		C050414
CTD	decreases(expression)		SESN1		C050414
CTD	increases(expression)		SLC3A2		C050414
CTD	decreases(response to substance)		SLC7A11		C050414
CTD	increases(expression)		SLC7A11		C050414
CTD	decreases(expression)		SLTM		C050414
CTD	decreases(expression)		SOX4		C050414
CTD	increases(expression)		STIP1		C050414
CTD	decreases(expression)		TAOK3		C050414
CTD	decreases(expression)		TMPRSS2		C050414
CTD	affects(localization)		TNF		C050414
CTD	decreases(reaction)		TNF		C050414
CTD	increases(activity)		TNF		C050414
CTD	increases(expression)		TNF		C050414
CTD	affects(cotreatment)		TNFRSF10A		C050414
CTD	increases(cleavage)		TNFRSF10A		C050414
CTD	increases(reaction)		TNFRSF10A		C050414
CTD	increases(expression)		TNFRSF10A		C050414
CTD	increases(localization)		TNFRSF10A		C050414
CTD	affects(cotreatment)		TNFRSF10B		C050414
CTD	increases(cleavage)		TNFRSF10B		C050414
CTD	increases(reaction)		TNFRSF10B		C050414
CTD	increases(expression)		TNFRSF10B		C050414
CTD	increases(localization)		TNFRSF10B		C050414
CTD	affects(cotreatment)		TNFSF10		C050414
CTD	increases(cleavage)		TNFSF10		C050414
CTD	increases(reaction)		TNFSF10		C050414
CTD	increases(response to substance)		TNFSF10		C050414
CTD	decreases(expression)		TXNIP		C050414
CTD	increases(expression)		TXNRD1		C050414
CTD	increases(expression)		UBE2B		C050414
CTD	increases(expression)		UGDH		C050414
CTD	decreases(reaction)		VCAM1		C050414
CTD	increases(expression)		VCAM1		C050414
CTD	decreases(expression)		WDR77		C050414
CTD	decreases(expression)		ZBTB43		C050414
CTD	decreases(expression)		ZC3H12A		C050414
PubChem	None	uM	PTGER2	-	GI(Protien) :
ChEMBL	Activity	-	HSP90AB1	-	Target : CHEMBL4303

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