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Gene Set: D4 : CTD - N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine

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Collection	D4 : CTD
Chemical Name	N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine ( From PubChem : TPEN )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Not Not Not Not Not Not Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 424.541 g/mol 0 6 3.9712 True
Structure
InChI	InChI=1S/C26H28N6/c1-5-13-27-23(9-1)19-31(20-24-10-2-6-14-28-24)17-18-32(21-25-11-3-7-15-29-25)22-26-12-4-8-16-30-26/h1-16H,17-22H2
InChIKey	CVRXLMUYFMERMJ-UHFFFAOYSA-N
Links
Gene (253 / 367) ⊖ Less	Source Type Unit Value Gene PMID Assay Other CTD decreases(expression) AARS C044387 CTD decreases(expression) ABCC10 C044387 CTD increases(expression) ABCC9 C044387 CTD decreases(expression) ABL1 C044387 CTD decreases(expression) ACADL C044387 CTD decreases(reaction) ACADL C044387 CTD affects(cotreatment) AIFM1 C044387 CTD affects(localization) AIFM1 C044387 CTD decreases(reaction) AIFM1 C044387 CTD increases(expression) AP2B1 C044387 CTD increases(expression) APC2 C044387 CTD decreases(expression) APOB C044387 CTD decreases(reaction) APOB C044387 CTD decreases(expression) ARHGEF18 C044387 CTD increases(expression) AZIN1 C044387 CTD decreases(reaction) BAX C044387 CTD increases(expression) BAX C044387 CTD decreases(expression) BBC3 C044387 CTD increases(expression) BBS9 C044387 CTD decreases(expression) BCL2 C044387 CTD decreases(reaction) BCL2 C044387 CTD decreases(expression) BCL2L1 C044387 CTD decreases(reaction) BCL2L1 C044387 CTD decreases(expression) BRD1 C044387 CTD decreases(expression) BRD3 C044387 CTD decreases(expression) BRD8 C044387 CTD increases(expression) C10ORF54 C044387 CTD decreases(expression) C11ORF95 C044387 CTD decreases(expression) C1ORF50 C044387 CTD decreases(expression) CAMSAP1 C044387 CTD increases(expression) CASP1 C044387 CTD affects(cotreatment) CASP3 C044387 CTD increases(activity) CASP3 C044387 CTD affects(reaction) CASP3 C044387 CTD increases(activity) CASP3 C044387 CTD decreases(reaction) CASP3 C044387 CTD increases(cleavage) CASP3 C044387 CTD decreases(expression) CASP3 C044387 CTD increases(activity) CASP3 C044387 CTD increases(expression) CASP3 C044387 CTD increases(activity) CASP8 C044387 CTD increases(activity) CASP9 C044387 CTD decreases(expression) CCDC130 C044387 CTD increases(expression) CCL2 C044387 CTD increases(expression) CCL22 C044387 CTD increases(expression) CCL3 C044387 CTD increases(expression) CCND1 C044387 CTD increases(expression) CCR1 C044387 CTD decreases(expression) CCR2 C044387 CTD increases(expression) CCR2 C044387 CTD increases(expression) CD14 C044387 CTD increases(reaction) CD14 C044387 CTD affects(cotreatment) CD14 C044387 CTD decreases(reaction) CD14 C044387 CTD decreases(expression) CD58 C044387 CTD affects(cotreatment) CDH1 C044387 CTD increases(cleavage) CDH1 C044387 CTD decreases(reaction) CDH1 C044387 CTD decreases(expression) CEBPD C044387 CTD increases(expression) CFP C044387 CTD decreases(expression) CLCN7 C044387 CTD increases(expression) CLCNKB C044387 CTD affects(binding) CREBBP C044387 CTD decreases(reaction) CREBBP C044387 CTD decreases(expression) CRYZ C044387 CTD decreases(expression) CTDP1 C044387 CTD decreases(expression) CTDSP2 C044387 CTD affects(cotreatment) CTNNB1 C044387 CTD increases(cleavage) CTNNB1 C044387 CTD decreases(reaction) CTNNB1 C044387 CTD increases(expression) CTSK C044387 CTD increases(expression) CX3CR1 C044387 CTD increases(expression) CXCL2 C044387 CTD increases(secretion) CXCL8 C044387 CTD decreases(expression) CYTH4 C044387 CTD decreases(expression) DAD1 C044387 CTD decreases(expression) DDX23 C044387 CTD decreases(expression) DGCR14 C044387 CTD decreases(expression) DGCR2 C044387 CTD decreases(expression) DGKZ C044387 CTD increases(expression) DHX58 C044387 CTD decreases(expression) DICER1 C044387 CTD increases(expression) DSTN C044387 CTD decreases(expression) DYNC1LI2 C044387 CTD increases(expression) EGFL7 C044387 CTD increases(activity) EGLN1 C044387 CTD decreases(reaction) EGLN1 C044387 CTD increases(activity) EGLN1 C044387 CTD decreases(expression) EHD1 C044387 CTD decreases(expression) ELF4 C044387 CTD decreases(expression) FADD C044387 CTD increases(expression) FAM13A C044387 CTD increases(expression) FEZ1 C044387 CTD decreases(expression) FOXO3 C044387 CTD decreases(expression) FRAT2 C044387 CTD decreases(expression) FZR1 C044387 CTD decreases(expression) G6PD C044387 CTD decreases(expression) GGA2 C044387 CTD decreases(expression) GMIP C044387 CTD decreases(expression) GOLPH3L C044387 CTD decreases(expression) GORASP2 C044387 CTD decreases(expression) GSTA1 C044387 CTD increases(expression) HAX1 C044387 CTD decreases(expression) HIC2 C044387 CTD affects(binding) HIF1A C044387 CTD decreases(reaction) HIF1A C044387 CTD decreases(ubiquitination) HIF1A C044387 CTD increases(expression) HIF1A C044387 CTD increases(expression) HIF1A C044387 CTD increases(stability) HIF1A C044387 CTD increases(expression) HIST1H1C C044387 CTD increases(expression) HIST1H1D C044387 CTD increases(expression) HIST1H2BD C044387 CTD increases(expression) HIST1H2BE C044387 CTD increases(expression) HIST1H2BH C044387 CTD increases(expression) HIST1H2BK C044387 CTD increases(expression) HIST1H2BM C044387 CTD increases(expression) HIST1H3I C044387 CTD increases(expression) HIST1H4L C044387 CTD increases(expression) HIST2H2AA3 C044387 CTD increases(expression) HIST2H2BE C044387 CTD increases(expression) HLA-DPB1 C044387 CTD decreases(expression) HLX C044387 CTD decreases(expression) HMOX2 C044387 CTD decreases(activity) HNF4A C044387 CTD decreases(reaction) HNF4A C044387 CTD increases(expression) HNMT C044387 CTD increases(expression) IFI27 C044387 CTD increases(expression) IFI6 C044387 CTD affects(cotreatment) IFNG C044387 CTD increases(activity) IFNG C044387 CTD increases(cleavage) IFNG C044387 CTD decreases(reaction) IFNG C044387 CTD increases(secretion) IFNG C044387 CTD decreases(reaction) IFNG C044387 CTD increases(expression) IFNGR1 C044387 CTD decreases(expression) IFNGR2 C044387 CTD decreases(reaction) IL10 C044387 CTD decreases(secretion) IL10 C044387 CTD decreases(expression) IL10 C044387 CTD increases(expression) IL10RA C044387 CTD increases(expression) IL10RB C044387 CTD increases(expression) IL13RA1 C044387 CTD increases(expression) IL1B C044387 CTD decreases(expression) IL4 C044387 CTD decreases(expression) IL4R C044387 CTD increases(expression) IL4R C044387 CTD increases(secretion) IL6 C044387 CTD increases(expression) IL6R C044387 CTD decreases(expression) INTS6 C044387 CTD increases(expression) IQGAP2 C044387 CTD decreases(expression) IRF1 C044387 CTD increases(expression) ISG15 C044387 CTD increases(expression) ITGAM C044387 CTD increases(reaction) ITGAM C044387 CTD affects(cotreatment) ITGAM C044387 CTD decreases(reaction) ITGAM C044387 CTD decreases(expression) ITSN2 C044387 CTD decreases(reaction) JUN C044387 CTD increases(activity) JUN C044387 CTD decreases(expression) KAT6A C044387 CTD decreases(expression) KAZN C044387 CTD decreases(expression) KIF23 C044387 CTD increases(expression) KRT8 C044387 CTD decreases(reaction) KRT8 C044387 CTD decreases(expression) LAMP2 C044387 CTD decreases(expression) LATS2 C044387 CTD decreases(reaction) LATS2 C044387 CTD increases(expression) LILRA5 C044387 CTD increases(expression) LTA C044387 CTD decreases(expression) MAD2L1BP C044387 CTD decreases(expression) MAP2K5 C044387 CTD decreases(expression) MAPKBP1 C044387 CTD increases(expression) MBNL2 C044387 CTD decreases(expression) METTL10 C044387 CTD increases(expression) MMP10 C044387 CTD affects(binding) MMP9 C044387 CTD decreases(reaction) MMP9 C044387 CTD decreases(expression) MRPL12 C044387 CTD affects(cotreatment) MT1A C044387 CTD increases(expression) MT1A C044387 CTD decreases(reaction) MT1A C044387 CTD increases(expression) MT1A C044387 CTD affects(cotreatment) MT1B C044387 CTD increases(expression) MT1B C044387 CTD decreases(reaction) MT1E C044387 CTD increases(expression) MT1E C044387 CTD decreases(expression) MT1G C044387 CTD decreases(expression) MT1H C044387 CTD decreases(expression) MT1L C044387 CTD decreases(reaction) MT1X C044387 CTD increases(expression) MT1X C044387 CTD decreases(expression) MT1X C044387 CTD affects(cotreatment) MT2A C044387 CTD increases(expression) MT2A C044387 CTD decreases(reaction) MT2A C044387 CTD increases(expression) MT2A C044387 CTD decreases(reaction) MT2A C044387 CTD increases(expression) MT2A C044387 CTD decreases(reaction) MTF1 C044387 CTD increases(expression) MTF1 C044387 CTD increases(expression) MTF1 C044387 CTD decreases(expression) MTTP C044387 CTD decreases(reaction) MTTP C044387 CTD increases(expression) MX2 C044387 CTD decreases(expression) MYC C044387 CTD increases(expression) MYD88 C044387 CTD decreases(expression) NAB2 C044387 CTD increases(expression) NCBP2 C044387 CTD decreases(expression) NCLN C044387 CTD affects(localization) NFKB1 C044387 CTD decreases(reaction) NFKB1 C044387 CTD decreases(reaction) NFKBIA C044387 CTD increases(degradation) NFKBIA C044387 CTD decreases(expression) NFKBIA C044387 CTD decreases(expression) NKX3-2 C044387 CTD increases(expression) NLGN1 C044387 CTD decreases(expression) NLRX1 C044387 CTD decreases(expression) NSMCE4A C044387 CTD increases(expression) NUP50 C044387 CTD decreases(expression) OGT C044387 CTD affects(reaction) PARP1 C044387 CTD increases(cleavage) PARP1 C044387 CTD decreases(expression) PIK3C3 C044387 CTD increases(expression) PLSCR1 C044387 CTD decreases(expression) POLR2A C044387 CTD decreases(expression) POLR2D C044387 CTD decreases(expression) PON2 C044387 CTD increases(expression) POU4F2 C044387 CTD decreases(activity) PPARA C044387 CTD decreases(reaction) PPARA C044387 CTD decreases(expression) PPP2R2D C044387 CTD increases(expression) PSMB2 C044387 CTD increases(expression) PTCRA C044387 CTD increases(expression) PTP4A1 C044387 CTD increases(expression) PTPRN C044387 CTD decreases(expression) PUS1 C044387 CTD decreases(expression) QRICH1 C044387 CTD increases(expression) RAD51 C044387 CTD increases(expression) RAD51C C044387 CTD increases(expression) RB1 C044387 CTD decreases(reaction) RB1 C044387 CTD decreases(activity) RELA C044387 CTD decreases(reaction) RELA C044387 CTD decreases(expression) REPIN1 C044387 CTD decreases(expression) RGP1 C044387 CTD increases(expression) RIMS2 C044387 CTD decreases(expression) RNF187 C044387 CTD increases(expression) ROR1 C044387 CTD decreases(expression) RPL10 C044387 CTD increases(expression) RPRM C044387 CTD decreases(reaction) RPRM C044387 CTD decreases(expression) RPS2P45 C044387 CTD increases(expression) RPS6KA2 C044387 CTD increases(expression) RRH C044387 CTD increases(expression) S100A12 C044387 CTD increases(expression) S100A4 C044387 CTD increases(expression) S100A6 C044387 CTD increases(expression) S100A8 C044387 CTD increases(expression) S100A9 C044387 CTD decreases(expression) S100P C044387 CTD increases(expression) SCG3 C044387 CTD decreases(expression) SEC16A C044387 CTD decreases(expression) SESN1 C044387 CTD increases(expression) SFN C044387 CTD decreases(reaction) SFN C044387 CTD decreases(expression) SIDT2 C044387 CTD increases(expression) SLC11A2 C044387 CTD decreases(expression) SLC25A39 C044387 CTD decreases(reaction) SLC30A1 C044387 CTD increases(expression) SLC30A1 C044387 CTD decreases(expression) SLC30A1 C044387 CTD decreases(expression) SLC30A1 C044387 CTD increases(reaction) SLC30A1 C044387 CTD affects(cotreatment) SLC30A1 C044387 CTD increases(expression) SLC30A1 C044387 CTD decreases(reaction) SLC30A1 C044387 CTD affects(cotreatment) SLC30A5 C044387 CTD decreases(expression) SLC30A5 C044387 CTD decreases(expression) SLC30A5 C044387 CTD increases(expression) SLC30A5 C044387 CTD affects(cotreatment) SLC30A6 C044387 CTD decreases(expression) SLC30A6 C044387 CTD increases(expression) SLC30A6 C044387 CTD affects(cotreatment) SLC30A7 C044387 CTD decreases(expression) SLC30A7 C044387 CTD increases(expression) SLC30A7 C044387 CTD increases(reaction) SLC30A7 C044387 CTD increases(expression) SLC30A7 C044387 CTD increases(expression) SLC39A1 C044387 CTD affects(cotreatment) SLC39A10 C044387 CTD decreases(expression) SLC39A10 C044387 CTD affects(cotreatment) SLC39A14 C044387 CTD decreases(expression) SLC39A14 C044387 CTD decreases(expression) SLC39A2 C044387 CTD increases(expression) SLC39A2 C044387 CTD increases(expression) SLC39A4 C044387 CTD decreases(expression) SLC39A6 C044387 CTD decreases(reaction) SLC39A6 C044387 CTD increases(cleavage) SLC39A6 C044387 CTD increases(expression) SLC39A6 C044387 CTD decreases(response to substance) SLC39A6 C044387 CTD decreases(expression) SLC7A1 C044387 CTD decreases(expression) SLC9A6 C044387 CTD decreases(expression) SLCO1C1 C044387 CTD decreases(expression) SMIM7 C044387 CTD increases(expression) SOD1 C044387 CTD decreases(expression) SPEN C044387 CTD decreases(reaction) SRC C044387 CTD increases(phosphorylation) SRC C044387 CTD increases(expression) SRSF5 C044387 CTD increases(expression) STAT1 C044387 CTD decreases(expression) STAT3 C044387 CTD decreases(reaction) STAT3 C044387 CTD increases(expression) STEAP4 C044387 CTD decreases(expression) STK10 C044387 CTD decreases(expression) SYNRG C044387 CTD decreases(expression) TBC1D8 C044387 CTD decreases(expression) TGFBR2 C044387 CTD decreases(expression) THOP1 C044387 CTD increases(expression) TIMP3 C044387 CTD decreases(reaction) TIMP3 C044387 CTD decreases(expression) TLE1 C044387 CTD increases(expression) TMEM184C C044387 CTD affects(cotreatment) TNF C044387 CTD increases(activity) TNF C044387 CTD increases(cleavage) TNF C044387 CTD affects(cotreatment) TNF C044387 CTD increases(reaction) TNF C044387 CTD increases(secretion) TNF C044387 CTD decreases(reaction) TNF C044387 CTD decreases(expression) TNFAIP8 C044387 CTD decreases(expression) TNS3 C044387 CTD affects(cotreatment) TP53 C044387 CTD decreases(expression) TP53 C044387 CTD decreases(reaction) TP53 C044387 CTD affects(localization) TP53 C044387 CTD increases(expression) TP53 C044387 CTD decreases(expression) TP53 C044387 CTD decreases(reaction) TP53 C044387 CTD increases(expression) TP53 C044387 CTD increases(expression) TP73 C044387 CTD decreases(reaction) TP73 C044387 CTD decreases(expression) TRAK1 C044387 CTD decreases(expression) TST C044387 CTD increases(expression) TXNIP C044387 CTD increases(expression) TYMS C044387 CTD decreases(expression) UGCG C044387 CTD increases(expression) UNG C044387 CTD decreases(expression) USP24 C044387 CTD increases(expression) UVRAG C044387 CTD decreases(expression) VEGFA C044387 CTD increases(secretion) VEGFA C044387 CTD decreases(expression) VPS33B C044387 CTD decreases(expression) WIPF2 C044387 CTD increases(expression) YWHAZ C044387 CTD decreases(reaction) YWHAZ C044387 CTD decreases(expression) ZCCHC8 C044387 CTD decreases(expression) ZFP36 C044387 CTD decreases(expression) ZFP64 C044387 CTD decreases(expression) ZNF512B C044387 CTD decreases(expression) ZNF764 C044387 CTD decreases(expression) ZNF816 C044387 PubChem None uM MITF - GI(Protien) : PubChem None uM STK33 - GI(Protien) : PubChem Potency uM 5.603 TDP1 - GI(Protien) : PubChem Potency uM 9.963 TDP1 - GI(Protien) :
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