Tan Lab | DSigDB

Gene Set: D4 : TTD - (Z)-3-((1H-pyrrol-2-yl)methylene)indolin-2-one

Collection

D4 : TTD

Chemical Name

(Z)-3-((1H-pyrrol-2-yl)methylene)indolin-2-one ( From PubChem : OXINDOLE I )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
210.231 g/mol	2	2	2.6454	True

Structure

InChI

InChI=1S/C13H10N2O/c16-13-11(8-9-4-3-7-14-9)10-5-1-2-6-12(10)15-13/h1-8,14H,(H,15,16)/b11-8-

InChIKey

SEZFNTZQMWJIAI-FLIBITNWSA-N

Links

Gene (15 / 15)

⊖ Less

Source	Type	Unit	Gene	PMID	Other
TTD	Inhibitor		AKT1		Clinical trial target
TTD	Inhibitor		AKT2		Clinical trial target
TTD	Inhibitor		AKT3		Clinical trial target
TTD	Inhibitor		PDPK1		Research target
TTD	Inhibitor		RET		Successful target
PubChem	None	uM	MAP3K5	-	GI(Protien) :
PubChem	None	uM	SLK	-	GI(Protien) :
PubChem	None	uM	STK16	-	GI(Protien) :
ChEMBL	Activity	-	CDK16	-	Target : CHEMBL4597
ChEMBL	Activity	-	CSNK1D	-	Target : CHEMBL2828
ChEMBL	Activity	-	CSNK1E	-	Target : CHEMBL4937
ChEMBL	Activity	-	KDR	-	Target : CHEMBL279
ChEMBL	Activity	-	KIT	-	Target : CHEMBL1936
ChEMBL	Activity	-	PDGFRB	-	Target : CHEMBL1913
ChEMBL	Activity	-	STK3	-	Target : CHEMBL4708

Download gene sets

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Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

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