Tan Lab | DSigDB

Gene Set: D4 : TTD - Oxiconazole

Collection

D4 : TTD

Chemical Name

Oxiconazole ( From PubChem : OXICONAZOLE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Approved	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
429.127 g/mol	0	4	6.1178	False(3/4)

Structure

InChI

InChI=1S/C18H13Cl4N3O/c19-13-2-1-12(16(21)7-13)10-26-24-18(9-25-6-5-23-11-25)15-4-3-14(20)8-17(15)22/h1-8,11H,9-10H2/b24-18+

InChIKey

Links

Gene (13 / 17)

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Source	Type	Unit	Value	Gene	PMID	Other
TTD	Inhibitor			CYP51A1		Successful target
TTD	Drug(s)			CYP51A1		Successful target
PubChem	None	uM		MITF	-	GI(Protien) :
PubChem	None	uM		STK33	-	GI(Protien) :
PubChem	AhR Potency (uM)	uM	10.591	AHR	-	GI(Protien) :
PubChem	AR Potency (uM)	uM	26.603	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	2.660	CYP19A1	-	GI(Protien) :
PubChem	None	uM		CYP19A1	-	GI(Protien) :
PubChem	Potency	uM	0.200	CYP3A4	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	11.883	ESR1	-	GI(Protien) :
PubChem	ER Potency (uM)	uM	19.570	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	29.847	HSPB1	-	GI(Protien) :
PubChem	None	uM		MDM2	-	GI(Protien) :
PubChem	None	uM		MDM4	-	GI(Protien) :
PubChem	None	uM		PPP1CA	-	GI(Protien) :
PubChem	None	uM		UBE2N	-	GI(Protien) :
ChEMBL	Potency	nM	199.500	CYP3A4	-	Target : CHEMBL340

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