Gene Set: D4 : TTD - AZD-2281
| Collection |
D4 : TTD |
| Chemical Name |
AZD-2281 ( From PubChem : O L A P A R I B ) |
| FDA |
NPC |
WHO |
Indian |
Australia |
China |
Traditional
Herbal |
Clinical
Trail |
| Not | Not | Not | Not | Not | Not | Not | Not |
|
Molecular
Weight |
Hydrogen Bond
Donor Count |
Hydrogen Bond
Acceptor Count |
cLogP |
Lipinski Rule |
| 434.463 g/mol |
1 |
6 |
2.2232 |
True |
|
| Structure |
|
| InChI |
I n C h I = 1 S / C 2 4 H 2 3 F N 4 O 3 / c 2 5 - 2 0 - 8 - 5 - 1 5 ( 1 4 - 2 1 - 1 7 - 3 - 1 - 2 - 4 - 1 8 ( 1 7 ) 2 2 ( 3 0 ) 2 7 - 2 6 - 2 1 ) 1 3 - 1 9 ( 2 0 ) 2 4 ( 3 2 ) 2 9 - 1 1 - 9 - 2 8 ( 1 0 - 1 2 - 2 9 ) 2 3 ( 3 1 ) 1 6 - 6 - 7 - 1 6 / h 1 - 5 , 8 , 1 3 , 1 6 H , 6 - 7 , 9 - 1 2 , 1 4 H 2 , ( H , 2 7 , 3 0 ) |
| InChIKey |
F D L Y A M Z Z I X Q O D N - U H F F F A O Y S A - N
|
| Links |
|
Gene
(1 /
6)
⊖ Less
|
| Source | Type | Unit | Value | Gene | PMID | Assay | Other | | TTD | Inhibitor | PARP1 | | | Successful target | | TTD | Inhibitor | PARP1 | | | Successful target | | TTD | Inhibitor | PARP1 | | | Successful target | | TTD | Drug(s) | PARP1 | | | Successful target | | TTD | Drug(s) | PARP1 | | | Successful target | | ChEMBL | Activity | - | | PARP1
| - |  | Target : CHEMBL3105 |
|
| Download gene sets |
gmt, text, Detailed text
|
Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA
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