Tan Lab | DSigDB

Gene Set: D4 : TTD - Okadaic acid

Collection

D4 : TTD

Chemical Name

Okadaic acid ( From PubChem : OKADAIC ACID )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
805.003 g/mol	5	13	5.2136	False(1/4)

Structure

InChI

InChI=1S/C44H68O13/c1-25-21-34(55-44(23-25)35(46)12-11-31(54-44)24-41(6,50)40(48)49)26(2)9-10-30-14-18-43(53-30)19-15-33-39(57-43)36(47)29(5)38(52-33)32(45)22-28(4)37-27(3)13-17-42(56-37)16-7-8-20-51-42/h9-10,23,26-28,30-39,45-47,50H,5,7-8,11-22,24H2,1-4,6H3,(H,48,49)

InChIKey

QNDVLZJODHBUFM-UHFFFAOYSA-N

Links

Gene (11 / 18)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
TTD	Inhibitor			DUSP1		Research target
TTD	Inhibitor			IGF1R		Successful target
TTD	Drug(s)			IGF1R		Successful target
PubChem	Potency	uM	0.052	ATAD5	-	GI(Protien) :
PubChem	None	uM		DRD3	-	GI(Protien) :
PubChem	None	uM		HCRTR1	-	GI(Protien) :
PubChem	None	uM		MDM2	-	GI(Protien) :
PubChem	None	uM		MDM2	-	GI(Protien) :
PubChem	None	uM		MDM4	-	GI(Protien) :
PubChem	None	uM		MDM4	-	GI(Protien) :
PubChem	Potency	uM	0.021	SMAD3	-	GI(Protien) :
PubChem	Potency	uM	0.082	SMAD3	-	GI(Protien) :
PubChem	Potency	uM	0.089	SMAD3	-	GI(Protien) :
PubChem	Potency	uM	0.146	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.164	TDP1	-	GI(Protien) :
PubChem	None	uM		TSHR		GI(Protien) :
PubChem	None	uM		TSHR		GI(Protien) :
ChEMBL	Drug metabolism	-		CYP3A4	-	Target : CHEMBL340

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