Tan Lab | DSigDB

Gene Set: D4 : TTD - NSC-663284

Collection

D4 : TTD

Chemical Name

NSC-663284 ( From PubChem : NSC 663284 )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
321.759 g/mol	1	6	1.1616	True

Structure

InChI

InChI=1S/C15H16ClN3O3/c16-11-13(18-4-5-19-6-8-22-9-7-19)15(21)12-10(14(11)20)2-1-3-17-12/h1-3,18H,4-9H2

InChIKey

Links

Gene (8 / 21)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
TTD	Inhibitor			CDC25C		Research target
PubChem	Potency	uM	3.548	BLM	-	GI(Protien) :
PubChem	Potency	uM	5.012	BLM	-	GI(Protien) :
PubChem	Potency	uM	5.759	BLM	-	GI(Protien) :
PubChem	Potency	uM	2.512	CASP1	-	GI(Protien) :
PubChem	Potency	uM	6.310	CASP1	-	GI(Protien) :
PubChem	Potency	uM	2.512	CYP3A4	-	GI(Protien) :
PubChem	Potency	uM	12.589	MAPT	-	GI(Protien) :
PubChem	Potency	uM	3.162	TP53	-	GI(Protien) :
PubChem	Potency	uM	5.012	TP53	-	GI(Protien) :
PubChem	None	uM		WHSC1	-	GI(Protien) :
PubChem	Potency	uM	6.883	YES1		GI(Protien) :
ChEMBL	Potency	nM	5011.900	BLM	-	Target : CHEMBL1293237
ChEMBL	Potency	nM	3548.100	BLM	-	Target : CHEMBL1293237
ChEMBL	Potency	nM	5759.100	BLM	-	Target : CHEMBL1293237
ChEMBL	Potency	nM	6309.600	CASP1	-	Target : CHEMBL4801
ChEMBL	Potency	nM	2511.900	CASP1	-	Target : CHEMBL4801
ChEMBL	Potency	nM	2511.900	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	12589.300	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	5011.900	TP53	-	Target : CHEMBL4096
ChEMBL	Potency	nM	3162.300	TP53	-	Target : CHEMBL4096

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