Tan Lab | DSigDB

Gene Set: D4 : TTD - Norgestimate

Collection

D4 : TTD

Chemical Name

Norgestimate ( From PubChem : NORGESTIMATE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
369.497 g/mol	1	4	4.7145	True

Structure

InChI

InChI=1S/C23H31NO3/c1-4-22-12-10-19-18-9-7-17(24-26)14-16(18)6-8-20(19)21(22)11-13-23(22,5-2)27-15(3)25/h2,14,18-21,26H,4,6-13H2,1,3H3/b24-17+/t18-,19+,20+,21-,22-,23-/m0/s1

InChIKey

KIQQMECNKUGGKA-NMYWJIRASA-N

Links

Gene (7 / 15)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
TTD	Agonist			PGR		Successful target
TTD	Drug(s)			PGR		Successful target
PubChem	Potency-Replicate_1	uM	0.030	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.085	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.150	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	20.122	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	29.849	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	23.710	CYP19A1	-	GI(Protien) :
PubChem	None	uM		DRD3	-	GI(Protien) :
PubChem	None	uM		DRD3	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.106	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.673	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.952	ESR1	-	GI(Protien) :
PubChem	None	uM		NR3C1	-	GI(Protien) :
PubChem	Potency	uM	18.837	TDP1	-	GI(Protien) :

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