Tan Lab | DSigDB

Gene Set: D4 : TTD - DEMETHYL-CANTHARIDIN

Collection

D4 : TTD

Chemical Name

DEMETHYL-CANTHARIDIN ( From PubChem : NORCANTHARIDIN )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
168.147 g/mol	0	4	-0.1366	True

Structure

InChI

InChI=1S/C8H8O4/c9-7-5-3-1-2-4(11-3)6(5)8(10)12-7/h3-6H,1-2H2/t3-,4+,5-,6+

InChIKey

JAABVEXCGCXWRR-FBXFSONDSA-N

Links

Gene (4 / 18)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
TTD	Inhibitor			PPP1CA		Research target
TTD	Inhibitor			PPP1CA		Research target
TTD	Inhibitor			PPP1CA		Research target
TTD	Inhibitor			PPP1CA		Research target
TTD	Inhibitor			PPP1CA		Research target
TTD	Inhibitor			PPP1CA		Research target
TTD	Inhibitor			PPP1CA		Research target
TTD	Inhibitor			PPP1CA		Research target
TTD	Inhibitor			PPP2R5A		Research target
PubChem	IC50	uM	2.832	PPP1CA	-	GI(Protien) :
PubChem	None	uM		PPP1CA	-	GI(Protien) :
PubChem	None	uM		PPP1CA	-	GI(Protien) :
PubChem	IC50	uM	2.567	PPP5C	-	GI(Protien) :
PubChem	None	uM		PPP5C	-	GI(Protien) :
PubChem	None	uM		PPP5C	-	GI(Protien) :
ChEMBL	Potency	nM	22387.200	KDM4E	-	Target : CHEMBL1293226
ChEMBL	IC50	nM	2832.000	PPP1CA	-	Target : CHEMBL2164
ChEMBL	IC50	nM	2567.000	PPP5C	-	Target : CHEMBL1293265

Download gene sets

gmt, text, Detailed text

Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

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