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Gene Set: D4 : TTD - SR-149415

Collection D4 : TTD
Chemical Name SR-149415 ( From PubChem : NELIVAPTAN )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotNotNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
630.108 g/mol 1 11 3.952 False(2/4)
Structure
InChI InChI=1S/C30H32ClN3O8S/c1-32(2)28(36)24-15-19(35)17-33(24)30(21-8-6-7-9-25(21)41-4)22-14-18(31)10-12-23(22)34(29(30)37)43(38,39)27-13-11-20(40-3)16-26(27)42-5/h6-14,16,19,24,35H,15,17H2,1-5H3/t19-,24+,30+/m1/s1
InChIKey NJXZWIIMWNEOGJ-WEWKHQNJSA-N
Links

Gene (8 / 12)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
TTDInhibitorAVPR1ASuccessful target
TTDAntagonistAVPR1BClinical trial target
TTDInhibitorAVPR1BClinical trial target
TTDDrug(s)AVPR1BClinical trial target
TTDInhibitorAVPR2Successful target
TTDInhibitorOXTRSuccessful target
PubChem Ratio Potency (uM)uM16.090AR-GI(Protien) :
PubChem Potency-Replicate_1uM17.374AR-GI(Protien) :
PubChem Potency-Replicate_1uM61.131CYP19A1-GI(Protien) :
PubChem Potency-Replicate_1uM43.641ESR1-GI(Protien) :
PubChem Ratio Potency (uM)uM54.941ESR1-GI(Protien) :
PubChem Ratio Potency (uM)uMNR1H4-GI(Protien) :
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