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Gene Set: D4 : TTD - ABT-263


Collection D4 : TTD
Chemical Name ABT-263 ( From PubChem : NAVITOCLAX )
FDA NPC WHO Indian Australia China Traditional
Herbal
Clinical
Trail
NotNotNotNotNotNotNotNot
Molecular
Weight
Hydrogen Bond
Donor Count
Hydrogen Bond
Acceptor Count
cLogP Lipinski Rule
974.613 g/mol 2 12 11.3995 False(1/4)
Structure
InChI InChI=1S/C47H55ClF3N5O6S3/c1-46(2)20-18-42(34-8-12-37(48)13-9-34)36(31-46)32-55-22-24-56(25-23-55)39-14-10-35(11-15-39)45(57)53-65(60,61)41-16-17-43(44(30-41)64(58,59)47(49,50)51)52-38(19-21-54-26-28-62-29-27-54)33-63-40-6-4-3-5-7-40/h3-17,30,38,52H,18-29,31-33H2,1-2H3,(H,53,57)/t38-/m1/s1
InChIKey JLYAXFNOILIKPP-KXQOOQHDSA-N
Links

Gene (7 / 16)


⊖ Less

Source Type Unit Value Gene PMID Assay Other
TTDMultitargetBCL2Clinical trial target
TTDInhibitorBCL2Clinical trial target
TTDDrug(s)BCL2Clinical trial target
TTDMultitargetBCL2L1Clinical trial target
TTDInhibitorBCL2L1Clinical trial target
TTDDrug(s)BCL2L1Clinical trial target
TTDMultitargetBCL2L2Clinical trial target
TTDInhibitorBCL2L2Clinical trial target
TTDDrug(s)BCL2L2Clinical trial target
PubChem PotencyuM39.811POLI-GI(Protien) :
PubChem PotencyuM67.016POLI-GI(Protien) :
PubChem PotencyuM44.668POLK-GI(Protien) :
PubChem PotencyuM0.316TDP1-GI(Protien) :
PubChem PotencyuM0.447TDP1-GI(Protien) :
PubChem PotencyuM30.747YES1GI(Protien) :
ChEMBLInhibition-BCL2
-Target : CHEMBL4860
Download gene sets gmt, text, Detailed text
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