Tan Lab | DSigDB

Gene Set: D4 : TTD - N-Omega-Propyl-L-Arginine

Collection

D4 : TTD

Chemical Name

N-Omega-Propyl-L-Arginine ( From PubChem : N-PLA )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
216.281 g/mol	4	6	1.2843	True

Structure

InChI

InChI=1S/C9H20N4O2/c1-2-5-12-9(11)13-6-3-4-7(10)8(14)15/h7H,2-6,10H2,1H3,(H,14,15)(H3,11,12,13)/t7-/m0/s1

InChIKey

AOMXURITGZJPKB-ZETCQYMHSA-N

Links

Gene (5 / 14)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
TTD	Inhibitor			NOS1		Clinical trial target
TTD	Inhibitor			NOS2		Successful target
PubChem	Potency	uM	1.995	CYP2C19	-	GI(Protien) :
PubChem	None	uM		CYP2C19	-	GI(Protien) :
PubChem	Potency	uM	3.981	CYP2C9	-	GI(Protien) :
PubChem	None	uM		CYP2C9	-	GI(Protien) :
PubChem	Potency	uM	7.943	CYP2D6	-	GI(Protien) :
PubChem	None	uM		CYP2D6	-	GI(Protien) :
ChEMBL	AC50	nM	1995.260	CYP2C19	-	Target : CHEMBL3622
ChEMBL	Potency	nM	1995.300	CYP2C19	-	Target : CHEMBL3622
ChEMBL	AC50	nM	3981.070	CYP2C9	-	Target : CHEMBL3397
ChEMBL	Potency	nM	3981.100	CYP2C9	-	Target : CHEMBL3397
ChEMBL	AC50	nM	7943.280	CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	7943.300	CYP2D6	-	Target : CHEMBL289

Download gene sets

gmt, text, Detailed text

Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

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