Tan Lab | DSigDB

Gene Set: D4 : TTD - 2-Methylamino-succinic acid(NMDA)

Collection

D4 : TTD

Chemical Name

2-Methylamino-succinic acid(NMDA) ( From PubChem : N-METHYL-D-ASPARTIC ACID )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
147.129 g/mol	3	5	-0.4754	True

Structure

InChI

InChI=1S/C5H9NO4/c1-6-3(5(9)10)2-4(7)8/h3,6H,2H2,1H3,(H,7,8)(H,9,10)/t3-/m1/s1

InChIKey

HOKKHZGPKSLGJE-GSVOUGTGSA-N

Links

Gene (10 / 12)

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Source	Type	Unit	Value	Gene	PMID	Other
TTD	Inhibitor			GRIN1		Research target
TTD	Inhibitor			GRIN2A		Successful target
TTD	Inhibitor			GRIN2B		Clinical trial target
PubChem	Potency	uM	22.387	EHMT2	-	GI(Protien) :
PubChem	None	uM		TNNC1	-	GI(Protien) :
PubChem	None	uM		TNNI3	-	GI(Protien) :
PubChem	None	uM		TNNT2	-	GI(Protien) :
PubChem	Potency	uM	0.794	TSHR	-	GI(Protien) :
ChEMBL	Potency	nM	22387.200	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	25118.900	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	22387.200	KDM4A	-	Target : CHEMBL5896
ChEMBL	Potency	nM	794.300	TSHR	-	Target : CHEMBL1963

Download gene sets

gmt, text, Detailed text

Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

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