Tan Lab | DSigDB

Gene Set: D4 : TTD - 4-Aminopyridine

Collection

D4 : TTD

Chemical Name

4-Aminopyridine ( From PubChem : 4-AMINOPYRIDINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
94.1145 g/mol	1	2	1.245	True

Structure

InChI

InChI=1S/C5H6N2/c6-5-1-3-7-4-2-5/h1-4H,(H2,6,7)

InChIKey

NUKYPUAOHBNCPY-UHFFFAOYSA-N

Links

Gene (3 / 8)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
TTD	Drug(s)			KCNA5		Clinical trial target
TTD	Blocker			KCNA5		Clinical trial target
TTD	Drug(s)			KCNJ5		Successful target
TTD	Blocker			KCNJ5		Successful target
PubChem	Potency	uM	0.063	CYP2D6	-	GI(Protien) :
PubChem	None	uM		CYP2D6	-	GI(Protien) :
ChEMBL	AC50	nM	63.100	CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	63.100	CYP2D6	-	Target : CHEMBL289

Download gene sets

gmt, text, Detailed text

Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

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