Tan Lab | DSigDB

Gene Set: D4 : TTD - MORIN

Collection

D4 : TTD

Chemical Name

MORIN ( From PubChem : MORIN )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
302.236 g/mol	5	7	1.988	True

Structure

InChI

InChI=1S/C15H10O7/c16-6-1-2-8(9(18)3-6)15-14(21)13(20)12-10(19)4-7(17)5-11(12)22-15/h1-5,16-19,21H

InChIKey

YXOLAZRVSSWPPT-UHFFFAOYSA-N

Links

Gene (27 / 55)

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Source	Type	Unit	Value	Gene	PMID	Other
TTD	Inhibitor			ESR2		Successful target
TTD	Inhibitor			FASN		Successful target
TTD	Inhibitor			MCL1		Clinical trial target
TTD	Inhibitor			SLC22A12		Clinical trial target
PubChem	Potency	uM	50.119	BAZ2B	-	GI(Protien) :
PubChem	Potency	uM	39.811	CBX1	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	10.000	CYP2C9	-	GI(Protien) :
PubChem	Potency	uM	39.811	EHMT2	-	GI(Protien) :
PubChem	None	uM		ESR1	-	GI(Protien) :
PubChem	None	uM		ESR1	-	GI(Protien) :
PubChem	None	uM		ESR2	-	GI(Protien) :
PubChem	Potency	uM	8.494	EYA2	-	GI(Protien) :
PubChem	Potency	uM	2.378	FEN1	-	GI(Protien) :
PubChem	Potency	uM	2.378	FEN1	-	GI(Protien) :
PubChem	Potency	uM	28.184	FEN1	-	GI(Protien) :
PubChem	Potency	uM	3.162	GAA	-	GI(Protien) :
PubChem	Potency	uM	12.589	MAPT	-	GI(Protien) :
PubChem	Potency	uM	15.849	MAPT	-	GI(Protien) :
PubChem	IC50	uM	2.988	MCL1	-	GI(Protien) :
PubChem	None	uM		MCL1	-	GI(Protien) :
PubChem	Potency	uM	39.811	MPHOSPH8	-	GI(Protien) :
PubChem	None	uM		NCOA1	-	GI(Protien) :
PubChem	Potency	uM	0.562	POLB	-	GI(Protien) :
PubChem	Potency	uM	4.467	POLB	-	GI(Protien) :
PubChem	Potency	uM	7.943	POLH	-	GI(Protien) :
PubChem	Potency	uM	3.981	POLI	-	GI(Protien) :
PubChem	Potency	uM	50.119	POLI	-	GI(Protien) :
PubChem	Potency	uM	3.162	POLK	-	GI(Protien) :
PubChem	Potency	uM	4.228	POLK	-	GI(Protien) :
PubChem	Potency	uM	4.467	POLK	-	GI(Protien) :
PubChem	Potency	uM	22.387	POLK	-	GI(Protien) :
PubChem	None	uM		PPARG	-	GI(Protien) :
PubChem	Potency	uM	50.119	USP1	-	GI(Protien) :
PubChem	None	uM		VCP	-	GI(Protien) :
ChEMBL	Potency	nM	5011.900	APEX1	-	Target : CHEMBL5619
ChEMBL	Potency	nM	50118.700	BAZ2B	-	Target : CHEMBL1741220
ChEMBL	Potency	nM	39810.700	CBX1	-	Target : CHEMBL1741193
ChEMBL	Potency	nM	10000.000	CYP2C9	-	Target : CHEMBL3397
ChEMBL	Potency	nM	39810.700	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	2377.800	FEN1	-	Target : CHEMBL5027
ChEMBL	Potency	nM	3162.300	GAA	-	Target : CHEMBL2608
ChEMBL	Potency	nM	10000.000	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	12589.300	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	25118.900	KDM4E	-	Target : CHEMBL1293226
ChEMBL	Potency	nM	12589.300	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	15848.900	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	15848.900	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	28183.800	MAPT	-	Target : CHEMBL1293224
ChEMBL	IC50	nM	2988.260	MCL1	-	Target : CHEMBL4361
ChEMBL	Potency	nM	39810.700	MPHOSPH8	-	Target : CHEMBL1741210
ChEMBL	Potency	nM	562.300	POLB	-	Target : CHEMBL2392
ChEMBL	Potency	nM	4466.800	POLB	-	Target : CHEMBL2392
ChEMBL	Potency	nM	15848.900	RECQL	-	Target : CHEMBL1293236
ChEMBL	Potency	nM	7079.500	RECQL	-	Target : CHEMBL1293236

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