Tan Lab | DSigDB

Gene Set: D4 : TTD - MK2206

Collection

D4 : TTD

Chemical Name

MK2206 ( From PubChem : MK-2206 )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
407.467 g/mol	2	5	4.943	True

Structure

InChI

InChI=1S/C25H21N5O/c26-25(12-4-13-25)18-9-7-17(8-10-18)22-19(16-5-2-1-3-6-16)15-20-21(27-22)11-14-30-23(20)28-29-24(30)31/h1-3,5-11,14-15H,4,12-13,26H2,(H,29,31)

InChIKey

ULDXWLCXEDXJGE-UHFFFAOYSA-N

Links

Gene (7 / 19)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
TTD	Inhibitor			AKT1		Clinical trial target
TTD	Inhibitor			AKT1		Clinical trial target
TTD	Drug(s)			AKT1		Clinical trial target
TTD	Drug(s)			AKT1		Clinical trial target
TTD	Inhibitor			AKT2		Clinical trial target
TTD	Inhibitor			AKT2		Clinical trial target
TTD	Drug(s)			AKT2		Clinical trial target
TTD	Drug(s)			AKT2		Clinical trial target
TTD	Inhibitor			AKT3		Clinical trial target
TTD	Inhibitor			AKT3		Clinical trial target
TTD	Drug(s)			AKT3		Clinical trial target
TTD	Drug(s)			AKT3		Clinical trial target
PubChem	Potency-Replicate_1	uM	11.986	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	21.293	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM		ESR1	-	GI(Protien) :
PubChem	Potency	uM	7.943	SMAD3	-	GI(Protien) :
PubChem	Potency	uM	0.282	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.376	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.596	TDP1	-	GI(Protien) :

Download gene sets

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