Tan Lab | DSigDB

Gene Set: D4 : TTD - Mirtazapine

Collection

D4 : TTD

Chemical Name

Mirtazapine ( From PubChem : MIRTAZAPINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Not	Approved	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
265.353 g/mol	0	3	2.4818	True

Structure

InChI

InChI=1S/C17H19N3/c1-19-9-10-20-16(12-19)15-7-3-2-5-13(15)11-14-6-4-8-18-17(14)20/h2-8,16H,9-12H2,1H3/t16-/m0/s1

InChIKey

RONZAEMNMFQXRA-INIZCTEOSA-N

Links

Gene (4 / 14)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
TTD	Antagonist			HTR2C		Successful target
TTD	Drug(s)			HTR2C		Successful target
PubChem	Potency	uM	0.050	CYP2C19	-	GI(Protien) :
PubChem	None	uM		CYP2C19	-	GI(Protien) :
PubChem	Potency	uM	0.050	CYP2C9	-	GI(Protien) :
PubChem	None	uM		CYP2C9	-	GI(Protien) :
PubChem	Potency	uM	0.501	CYP2D6	-	GI(Protien) :
PubChem	None	uM		CYP2D6	-	GI(Protien) :
ChEMBL	Potency	nM	50.100	CYP2C19	-	Target : CHEMBL3622
ChEMBL	AC50	nM	50.120	CYP2C19	-	Target : CHEMBL3622
ChEMBL	AC50	nM	50.120	CYP2C9	-	Target : CHEMBL3397
ChEMBL	Potency	nM	50.100	CYP2C9	-	Target : CHEMBL3397
ChEMBL	AC50	nM	501.190	CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	501.200	CYP2D6	-	Target : CHEMBL289

Download gene sets

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Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

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