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Gene Set: D4 : TTD - Mevastatin

Collection D4 : TTD
Chemical Name Mevastatin ( From PubChem : MEVASTATIN )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotNotNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
390.513 g/mol 1 5 3.9495 True
Structure
InChI InChI=1S/C23H34O5/c1-4-14(2)23(26)28-20-7-5-6-16-9-8-15(3)19(22(16)20)11-10-18-12-17(24)13-21(25)27-18/h6,8-9,14-15,17-20,22,24H,4-5,7,10-13H2,1-3H3/t14-,15-,17+,18+,19-,20-,22-/m0/s1
InChIKey AJLFOPYRIVGYMJ-INTXDZFKSA-N
Links

Gene (11 / 13)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
TTDAntagonistHMGCRSuccessful target
PubChem Ratio Potency (uM)uM11.986AR-GI(Protien) :
PubChem Potency-Replicate_1uM15.089AR-GI(Protien) :
PubChem NoneuMCYP19A1-GI(Protien) :
PubChem NoneuMDRD2-GI(Protien) :
PubChem PotencyuM4.109IDH1-GI(Protien) :
PubChem NoneuMJAK2-GI(Protien) :
PubChem PotencyuM15.849NPSR1-GI(Protien) :
PubChem NoneuMNR0B1-GI(Protien) :
PubChem NoneuMNR3C1-GI(Protien) :
PubChem NoneuMSMARCA2-GI(Protien) :
PubChem PotencyuM14.581TDP1-GI(Protien) :
ChEMBLPotencynM15848.900NPSR1
-Target : CHEMBL5162
Download gene sets gmt, text, Detailed text
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