Tan Lab | DSigDB

Gene Set: D4 : TTD - 4-amino-1,8-naphthalimide

Collection

D4 : TTD

Chemical Name

4-amino-1,8-naphthalimide ( From PubChem : 4-AMINO-1,8-NAPHTHALIMIDE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
212.204 g/mol	2	3	1.6427	True

Structure

InChI

InChI=1S/C12H8N2O2/c13-9-5-4-8-10-6(9)2-1-3-7(10)11(15)14-12(8)16/h1-5H,13H2,(H,14,15,16)

InChIKey

Links

Gene (13 / 21)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
TTD	Inhibitor			PARP1		Successful target
TTD	Inhibitor			PARP1		Successful target
PubChem	Potency	uM	4.256	ARSA	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	11.220	DRD1	-	GI(Protien) :
PubChem	Potency	uM	0.794	GNAI1	-	GI(Protien) :
PubChem	None	uM		GNAI1	-	GI(Protien) :
PubChem	Potency	uM	31.623	HBB	-	GI(Protien) :
PubChem	Potency	uM	5.012	KCNH2		GI(Protien) :
PubChem	Potency	uM	5.012	KCNH2		GI(Protien) :
PubChem	Potency	uM	0.794	RGS12	-	GI(Protien) :
PubChem	None	uM		RGS12	-	GI(Protien) :
PubChem	None	uM		TRHR	-	GI(Protien) :
PubChem	Potency	uM	25.119	USP1	-	GI(Protien) :
ChEMBL	Potency	nM	12589.300	BRCA1	-	Target : CHEMBL5990
ChEMBL	AC50	nM	1000.000	CYP1A2	-	Target : CHEMBL3356
ChEMBL	Potency	nM	11220.200	DRD1	-	Target : CHEMBL2056
ChEMBL	Potency	nM	31622.800	HBB	-	Target : CHEMBL4331
ChEMBL	Potency	nM	25118.900	RECQL	-	Target : CHEMBL1293236
ChEMBL	Potency	nM	50118.700	TDP1	-	Target : CHEMBL1075138

Download gene sets