DSigDB Home
Search Gene
Collections
Browse Gene Sets
Download
Help

Gene Set: D4 : TTD - Melatonin

Collection D4 : TTD
Chemical Name Melatonin ( From PubChem : MELATONIN )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotNotNotApprovedNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
232.278 g/mol 2 3 2.246 True
Structure
InChI InChI=1S/C13H16N2O2/c1-9(16)14-6-5-10-8-15-13-4-3-11(17-2)7-12(10)13/h3-4,7-8,15H,5-6H2,1-2H3,(H,14,16)
InChIKey DRLFMBDRBRZALE-UHFFFAOYSA-N
Links

Gene (8 / 11)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
TTDDrug(s)MTNR1ASuccessful target
TTDInhibitorNQO2Clinical trial target
PubChem AhR Potency (uM)uM49.299AHR-GI(Protien) :
PubChem NoneuMCYP1A2-GI(Protien) :
PubChem NoneuMCYP1A2-GI(Protien) :
PubChem PotencyuM19.953CYP3A4-GI(Protien) :
PubChem Potency-Replicate_1uM55.315ESR1-GI(Protien) :
PubChem NoneuMHTR2BGI(Protien) :
PubChem NoneuMMAP4K2-GI(Protien) :
ChEMBLAC50nM5011.870CYP1A2
-Target : CHEMBL3356
ChEMBLPotencynM19952.600CYP3A4
-Target : CHEMBL340
Download gene sets gmt, text, Detailed text
Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

* Best viewed in the latest version of Chrome (42+), Safari (8+), IE (11+) or Firefox (35+).