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Gene Set: D4 : TTD - Ac-Nle-c[Asp-His-DPhe-Arg-Trp-Lys]-NH2


Collection D4 : TTD
Chemical Name Ac-Nle-c[Asp-His-DPhe-Arg-Trp-Lys]-NH2 ( From PubChem : MELANOTAN II )
FDA NPC WHO Indian Australia China Traditional
Herbal
Clinical
Trail
NotNotNotNotNotNotNotNot
Molecular
Weight
Hydrogen Bond
Donor Count
Hydrogen Bond
Acceptor Count
cLogP Lipinski Rule
1024.18 g/mol 13 22 3.6072 False(1/4)
Structure
InChI InChI=1S/C50H69N15O9/c1-3-4-16-36(59-29(2)66)44(69)65-41-25-42(67)55-20-11-10-18-35(43(51)68)60-47(72)39(23-31-26-57-34-17-9-8-15-33(31)34)63-45(70)37(19-12-21-56-50(52)53)61-46(71)38(22-30-13-6-5-7-14-30)62-48(73)40(64-49(41)74)24-32-27-54-28-58-32/h5-9,13-15,17,26-28,35-41,57H,3-4,10-12,16,18-25H2,1-2H3,(H2,51,68)(H,54,58)(H,55,67)(H,59,66)(H,60,72)(H,61,71)(H,62,73)(H,63,70)(H,64,74)(H,65,69)(H4,52,53,56)/t35-,36-,37-,38+,39-,40-,41-/m0/s1
InChIKey JDKLPDJLXHXHNV-MFVUMRCOSA-N
Links

Gene (3 / 4)


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Source Type Unit Value Gene PMID Assay Other
TTDInhibitorMC1RResearch target
TTDInhibitorMC3RResearch target
TTDAgonistMC4RClinical trial target
TTDInhibitorMC4RClinical trial target
Download gene sets gmt, text, Detailed text
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