Tan Lab | DSigDB

Gene Set: D4 : TTD - Marimastat

Collection

D4 : TTD

Chemical Name

Marimastat ( From PubChem : MARIMASTAT )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
331.408 g/mol	5	8	0.9646	True

Structure

InChI

InChI=1S/C15H29N3O5/c1-8(2)7-9(10(19)13(21)18-23)12(20)17-11(14(22)16-6)15(3,4)5/h8-11,19,23H,7H2,1-6H3,(H,16,22)(H,17,20)(H,18,21)/t9-,10+,11-/m1/s1

InChIKey

Links

Gene (6 / 21)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
TTD	Multitarget			MMP1		Discontinued target
TTD	Inhibitor			MMP1		Discontinued target
TTD	Drug(s)			MMP1		Discontinued target
TTD	Multitarget			MMP2		Discontinued target
TTD	Inhibitor			MMP2		Discontinued target
TTD	Drug(s)			MMP2		Discontinued target
TTD	Multitarget			MMP7		Discontinued target
TTD	Inhibitor			MMP7		Discontinued target
TTD	Drug(s)			MMP7		Discontinued target
PubChem	IC50	uM	0.036	ADAM10	-	GI(Protien) :
PubChem	IC50	uM	0.061	ADAM10	-	GI(Protien) :
PubChem	None	uM		ADAM10	-	GI(Protien) :
PubChem	None	uM		ADAM10	-	GI(Protien) :
PubChem	None	uM		ADAM10	-	GI(Protien) :
PubChem	IC50	uM	0.011	ADAM17	-	GI(Protien) :
PubChem	IC50	uM	0.025	ADAM17	-	GI(Protien) :
PubChem	None	uM		ADAM17	-	GI(Protien) :
PubChem	None	uM		ADAM17	-	GI(Protien) :
PubChem	None	uM		ADAM17	-	GI(Protien) :
PubChem	None	uM		PRNP	-	GI(Protien) :
PubChem	None	uM		PRNP	-	GI(Protien) :

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