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Gene Set: D4 : TTD - Losartan

Collection D4 : TTD
Chemical Name Losartan ( From PubChem : LOSARTAN )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
ApprovedNotNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
422.911 g/mol 2 6 4.2668 True
Structure
InChI InChI=1S/C22H23ClN6O/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22/h4-7,9-12,30H,2-3,8,13-14H2,1H3,(H,25,26,27,28)
InChIKey PSIFNNKUMBGKDQ-UHFFFAOYSA-N
Links

Gene (3 / 7)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
TTDAntagonistAGTR1Successful target
TTDDrug(s)AGTR1Successful target
PubChem PotencyuM19.953CYP3A4-GI(Protien) :
PubChem Ratio Potency (uM)uM16.930PPARG-GI(Protien) :
PubChem Potency-Replicate_1uM23.915PPARG-GI(Protien) :
ChEMBLActivity-AGTR1
-Target : CHEMBL227
ChEMBLPotencynM19952.600CYP3A4
-Target : CHEMBL340
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