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Gene Set: D4 : TTD - Letrozole

Collection D4 : TTD
Chemical Name Letrozole ( From PubChem : LETROZOLE )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
ApprovedNotNotApprovedApprovedNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
285.303 g/mol 0 5 2.65916 True
Structure
InChI InChI=1S/C17H11N5/c18-9-13-1-5-15(6-2-13)17(22-12-20-11-21-22)16-7-3-14(10-19)4-8-16/h1-8,11-12,17H
InChIKey HPJKCIUCZWXJDR-UHFFFAOYSA-N
Links

Gene (3 / 11)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
TTDInhibitorCYP19A1Successful target
TTDDrug(s)CYP19A1Successful target
PubChem Potency-Replicate_1uM0.009CYP19A1-GI(Protien) :
PubChem Potency-Replicate_1uM0.014CYP19A1-GI(Protien) :
PubChem NoneuMCYP19A1-GI(Protien) :
PubChem PotencyuM5.012CYP3A4-GI(Protien) :
PubChem NoneuMCYP3A4-GI(Protien) :
PubChem NoneuMDRD2-GI(Protien) :
ChEMBLInhibition-CYP19A1
-Target : CHEMBL1978
ChEMBLAC50nM5011.870CYP3A4
-Target : CHEMBL340
ChEMBLPotencynM5011.900CYP3A4
-Target : CHEMBL340
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