Tan Lab | DSigDB

Gene Set: D4 : TTD - LARGAZOLE

Collection

D4 : TTD

Chemical Name

LARGAZOLE ( From PubChem : LARGAZOLE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
622.863 g/mol	2	12	5.1275	False(1/4)

Structure

InChI

InChI=1S/C29H42N4O5S3/c1-5-6-7-8-9-13-24(35)39-14-11-10-12-20-15-22(34)30-16-23-31-21(17-40-23)26-33-29(4,18-41-26)28(37)32-25(19(2)3)27(36)38-20/h10,12,17,19-20,25H,5-9,11,13-16,18H2,1-4H3,(H,30,34)(H,32,37)/b12-10+/t20-,25+,29+/m1/s1

InChIKey

AXESYCSCGBQJBL-SZPBEECKSA-N

Links

Gene (5 / 27)

⊖ Less

Source	Type	Unit	Gene	PMID	Other
TTD	Inhibitor		HDAC1		Successful target
TTD	Inhibitor		HDAC4		Clinical trial target
ChEMBL	Activity	-	E2F1	-	Target : CHEMBL4382
ChEMBL	Activity	-	E2F1	-	Target : CHEMBL4382
ChEMBL	Activity	-	E2F1	-	Target : CHEMBL4382
ChEMBL	Activity	-	E2F1	-	Target : CHEMBL4382
ChEMBL	Activity	-	E2F1	-	Target : CHEMBL4382
ChEMBL	Activity	-	E2F1	-	Target : CHEMBL4382
ChEMBL	Inhibition	-	E2F1	-	Target : CHEMBL4382
ChEMBL	Inhibition	-	E2F1	-	Target : CHEMBL4382
ChEMBL	Activity	-	HDAC1	-	Target : CHEMBL325
ChEMBL	Inhibition	-	HDAC1	-	Target : CHEMBL325
ChEMBL	Inhibition	-	HDAC1	-	Target : CHEMBL325
ChEMBL	Inhibition	-	HDAC1	-	Target : CHEMBL325
ChEMBL	Inhibition	-	HDAC1	-	Target : CHEMBL325
ChEMBL	Inhibition	-	HDAC1	-	Target : CHEMBL325
ChEMBL	Inhibition	-	HDAC1	-	Target : CHEMBL325
ChEMBL	Inhibition	-	HDAC1	-	Target : CHEMBL325
ChEMBL	Inhibition	-	HDAC1	-	Target : CHEMBL325
ChEMBL	Inhibition	-	HDAC1	-	Target : CHEMBL325
ChEMBL	Inhibition	-	HDAC1	-	Target : CHEMBL325
ChEMBL	Inhibition	-	HDAC1	-	Target : CHEMBL325
ChEMBL	Inhibition	-	HDAC4	-	Target : CHEMBL3524
ChEMBL	Inhibition	-	HDAC6	-	Target : CHEMBL1865
ChEMBL	Activity	-	RB1	-	Target : CHEMBL5288
ChEMBL	Activity	-	RB1	-	Target : CHEMBL5288
ChEMBL	Activity	-	RB1	-	Target : CHEMBL5288

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