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Gene Set: D4 : TTD - Lamotrigine

Collection D4 : TTD
Chemical Name Lamotrigine ( From PubChem : LAMOTRIGINE )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
ApprovedNotNotApprovedApprovedNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
256.091 g/mol 2 5 3.1722 True
Structure
InChI InChI=1S/C9H7Cl2N5/c10-5-3-1-2-4(6(5)11)7-8(12)14-9(13)16-15-7/h1-3H,(H4,12,13,14,16)
InChIKey PYZRQGJRPPTADH-UHFFFAOYSA-N
Links

Gene (7 / 13)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
TTDDrug(s)SCN11ASuccessful target
TTDBlockerSCN11ASuccessful target
PubChem PotencyuM6.310CYP2D6-GI(Protien) :
PubChem NoneuMCYP2D6-GI(Protien) :
ChEMBLActivity-AQP4
-Target : CHEMBL5964
ChEMBLInhibition-CYP1A2
-Target : CHEMBL3356
ChEMBLInhibition-CYP2C19
-Target : CHEMBL3622
ChEMBLInhibition-CYP2C9
-Target : CHEMBL3397
ChEMBLInhibition-CYP2D6
-Target : CHEMBL289
ChEMBLPotencynM6309.600CYP2D6
-Target : CHEMBL289
ChEMBLAC50nM6309.570CYP2D6
-Target : CHEMBL289
ChEMBLInhibition-CYP3A4
-Target : CHEMBL340
ChEMBLInhibition-CYP3A4
-Target : CHEMBL340
Download gene sets gmt, text, Detailed text
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