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Gene Set: D4 : TTD - Ketotifen

Collection D4 : TTD
Chemical Name Ketotifen ( From PubChem : KETOTIFEN )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
ApprovedNotNotApprovedNotApprovedNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
309.425 g/mol 0 3 3.9523 True
Structure
InChI InChI=1S/C19H19NOS/c1-20-9-6-13(7-10-20)18-15-5-3-2-4-14(15)12-17(21)19-16(18)8-11-22-19/h2-5,8,11H,6-7,9-10,12H2,1H3
InChIKey ZCVMWBYGMWKGHF-UHFFFAOYSA-N
Links

Gene (3 / 14)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
TTDAntagonistHRH1Successful target
TTDDrug(s)HRH1Successful target
PubChem PotencyuM3.162CYP2D6-GI(Protien) :
PubChem PotencyuM5.012CYP2D6-GI(Protien) :
PubChem PotencyuM7.943CYP2D6-GI(Protien) :
PubChem NoneuMCYP2D6-GI(Protien) :
PubChem PotencyuM1.995DRD1-GI(Protien) :
ChEMBLAC50nM7943.280CYP2D6
-Target : CHEMBL289
ChEMBLAC50nM3162.280CYP2D6
-Target : CHEMBL289
ChEMBLAC50nM5011.870CYP2D6
-Target : CHEMBL289
ChEMBLPotencynM5011.900CYP2D6
-Target : CHEMBL289
ChEMBLPotencynM3162.300CYP2D6
-Target : CHEMBL289
ChEMBLPotencynM7943.300CYP2D6
-Target : CHEMBL289
ChEMBLPotencynM1995.300DRD1
-Target : CHEMBL2056
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