Tan Lab | DSigDB

Gene Set: D4 : TTD - Imetit

Collection

D4 : TTD

Chemical Name

Imetit ( From PubChem : IMETIT )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
170.235 g/mol	3	4	1.3789	True

Structure

InChI

InChI=1S/C6H10N4S/c7-6(8)11-2-1-5-3-9-4-10-5/h3-4H,1-2H2,(H3,7,8)(H,9,10)

InChIKey

PEHSVUKQDJULKE-UHFFFAOYSA-N

Links

Gene (6 / 17)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
TTD	Agonist			HRH3		Clinical trial target
TTD	Agonist			HRH4		Research target
PubChem	Potency	uM	6.310	CYP2D6	-	GI(Protien) :
PubChem	Potency	uM	25.119	CYP2D6	-	GI(Protien) :
PubChem	None	uM		CYP2D6	-	GI(Protien) :
PubChem	Potency	uM	15.849	CYP3A4	-	GI(Protien) :
PubChem	None	uM		CYP3A4	-	GI(Protien) :
PubChem	Potency	uM	7.519	EHMT2	-	GI(Protien) :
PubChem	Potency	uM	0.794	THPO	-	GI(Protien) :
ChEMBL	AC50	nM	25118.900	CYP2D6	-	Target : CHEMBL289
ChEMBL	AC50	nM	6309.570	CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	25118.900	CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	6309.600	CYP2D6	-	Target : CHEMBL289
ChEMBL	AC50	nM	15848.900	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	15848.900	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	7519.300	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	794.300	THPO	-	Target : CHEMBL1293256

Download gene sets

gmt, text, Detailed text

Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

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