Tan Lab | DSigDB

Gene Set: D4 : TTD - IMAZODAN

Collection

D4 : TTD

Chemical Name

IMAZODAN ( From PubChem : IMAZODAN )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
240.261 g/mol	1	5	1.2508	True

Structure

InChI

InChI=1S/C13H12N4O/c18-13-6-5-12(15-16-13)10-1-3-11(4-2-10)17-8-7-14-9-17/h1-4,7-9H,5-6H2,(H,16,18)

InChIKey

Links

Gene (11 / 24)

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Source	Type	Unit	Value	Gene	PMID	Other
TTD	Inhibitor			PDE2A		Research target
TTD	Inhibitor			PDE3A		Successful target
TTD	Inhibitor			PDE5A		Successful target
PubChem	Potency-Replicate_1	uM	5.956	AHR	-	GI(Protien) :
PubChem	AhR Potency (uM)	uM	13.333	AHR	-	GI(Protien) :
PubChem	None	uM		AHR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	6.682	CYP19A1	-	GI(Protien) :
PubChem	None	uM		CYP19A1	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	2.512	CYP2D6	-	GI(Protien) :
PubChem	None	uM		CYP2D6	-	GI(Protien) :
PubChem	Potency	uM	1.585	CYP3A4	-	GI(Protien) :
PubChem	None	uM		CYP3A4	-	GI(Protien) :
PubChem	None	uM		KCNQ1	-	GI(Protien) :
PubChem	None	uM		NR3C1	-	GI(Protien) :
PubChem	None	uM		SLC5A7	-	GI(Protien) :
PubChem	None	uM		SLC5A7	-	GI(Protien) :
PubChem	None	uM		SLC5A7	-	GI(Protien) :
ChEMBL	AC50	nM	158.490	CYP1A2	-	Target : CHEMBL3356
ChEMBL	AC50	nM	2511.890	CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	2511.900	CYP2D6	-	Target : CHEMBL289
ChEMBL	AC50	nM	1584.890	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	1584.900	CYP3A4	-	Target : CHEMBL340

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