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Gene Set: D4 : TTD - Ibudilast

Collection D4 : TTD
Chemical Name Ibudilast ( From PubChem : IBUDILAST )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotApprovedNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
230.306 g/mol 0 3 3.2964 True
Structure
InChI InChI=1S/C14H18N2O/c1-9(2)13-12(14(17)10(3)4)11-7-5-6-8-16(11)15-13/h5-10H,1-4H3
InChIKey ZJVFLBOZORBYFE-UHFFFAOYSA-N
Links

Gene (6 / 18)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
TTDMultitargetIL1BSuccessful target
TTDInhibitorIL1BSuccessful target
TTDDrug(s)IL1BSuccessful target
TTDMultitargetIL6Clinical trial target
TTDInhibitorIL6Clinical trial target
TTDDrug(s)IL6Clinical trial target
PubChem NoneuMCYP1A2-GI(Protien) :
PubChem NoneuMCYP1A2-GI(Protien) :
PubChem PotencyuM0.040CYP2D6-GI(Protien) :
PubChem NoneuMCYP2D6-GI(Protien) :
PubChem PotencyuM7.943CYP3A4-GI(Protien) :
PubChem NoneuMCYP3A4-GI(Protien) :
PubChem NoneuMPDE4B-GI(Protien) :
ChEMBLAC50nM630.960CYP1A2
-Target : CHEMBL3356
ChEMBLPotencynM39.800CYP2D6
-Target : CHEMBL289
ChEMBLAC50nM39.810CYP2D6
-Target : CHEMBL289
ChEMBLPotencynM7943.300CYP3A4
-Target : CHEMBL340
ChEMBLAC50nM7943.280CYP3A4
-Target : CHEMBL340
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