DSigDB Home
Search Gene
Collections
Browse Gene Sets
Download
Help

Gene Set: D4 : TTD - Hydroxyzine

Collection D4 : TTD
Chemical Name Hydroxyzine ( From PubChem : HYDROXYZINE )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
ApprovedNotNotApprovedNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
374.904 g/mol 1 4 2.9317 True
Structure
InChI InChI=1S/C21H27ClN2O2/c22-20-8-6-19(7-9-20)21(18-4-2-1-3-5-18)24-12-10-23(11-13-24)14-16-26-17-15-25/h1-9,21,25H,10-17H2/t21-/m1/s1
InChIKey ZQDWXGKKHFNSQK-OAQYLSRUSA-N
Links

Gene (6 / 8)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
TTDAntagonistHRH1Successful target
TTDDrug(s)HRH1Successful target
ChEMBLInhibition-CYP1A2
-Target : CHEMBL3356
ChEMBLInhibition-CYP2C19
-Target : CHEMBL3622
ChEMBLInhibition-CYP2C9
-Target : CHEMBL3397
ChEMBLInhibition-CYP2D6
-Target : CHEMBL289
ChEMBLInhibition-CYP3A4
-Target : CHEMBL340
ChEMBLInhibition-CYP3A4
-Target : CHEMBL340
Download gene sets gmt, text, Detailed text
Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

* Best viewed in the latest version of Chrome (42+), Safari (8+), IE (11+) or Firefox (35+).