Tan Lab | DSigDB

Gene Set: D4 : TTD - HINOKITIOL

Collection

D4 : TTD

Chemical Name

HINOKITIOL ( From PubChem : HINOKITIOL )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
164.201 g/mol	1	2	1.8758	True

Structure

InChI

InChI=1S/C10H12O2/c1-7(2)8-4-3-5-9(11)10(12)6-8/h3-7H,1-2H3,(H,11,12)

InChIKey

Links

Gene (10 / 24)

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Source	Type	Unit	Value	Gene	PMID	Other
TTD	Inhibitor			TYR		Successful target
PubChem	Potency	uM	56.234	BAZ2B	-	GI(Protien) :
PubChem	Potency	uM	11.220	EHMT2	-	GI(Protien) :
PubChem	IC50_Mean	uM	3.580	MDM2	-	GI(Protien) :
PubChem	None	uM		MDM2	-	GI(Protien) :
PubChem	None	uM		MDM2	-	GI(Protien) :
PubChem	None	uM		MDM2	-	GI(Protien) :
PubChem	IC50_Mean	uM	3.580	MDM4	-	GI(Protien) :
PubChem	None	uM		MDM4	-	GI(Protien) :
PubChem	None	uM		MDM4	-	GI(Protien) :
PubChem	None	uM		MDM4	-	GI(Protien) :
PubChem	None	uM		SLC12A5	-	GI(Protien) :
PubChem	None	uM		SLC12A5	-	GI(Protien) :
PubChem	Potency	uM	6.513	TDP1	-	GI(Protien) :
PubChem	Potency	uM	8.200	TDP1	-	GI(Protien) :
PubChem	Potency	uM	11.582	TDP1	-	GI(Protien) :
PubChem	Potency	uM	16.360	TDP1	-	GI(Protien) :
PubChem	Potency	uM	22.387	TDP1	-	GI(Protien) :
PubChem	None	uM		TTR	-	GI(Protien) :
ChEMBL	Potency	nM	12589.300	ALOX15B	-	Target : CHEMBL2457
ChEMBL	Potency	nM	56234.100	BAZ2B	-	Target : CHEMBL1741220
ChEMBL	Potency	nM	11220.200	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	7943.300	KDM4E	-	Target : CHEMBL1293226
ChEMBL	Potency	nM	25118.900	KDM4E	-	Target : CHEMBL1293226

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