Tan Lab | DSigDB

Gene Set: D4 : TTD - HESPERADIN

Collection

D4 : TTD

Chemical Name

HESPERADIN ( From PubChem : HESPERADIN )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
516.654 g/mol	3	7	6.6693	False(2/4)

Structure

InChI

InChI=1S/C29H32N4O3S/c1-2-37(35,36)32-24-15-16-26-25(19-24)27(29(34)31-26)28(22-9-5-3-6-10-22)30-23-13-11-21(12-14-23)20-33-17-7-4-8-18-33/h3,5-6,9-16,19,30,32H,2,4,7-8,17-18,20H2,1H3,(H,31,34)/b28-27-

InChIKey

GLDSKRNGVVYJAB-DQSJHHFOSA-N

Links

Gene (80 / 82)

⊖ Less

Source	Type	Unit	Gene	PMID	Other
TTD	Inhibitor		AURKB		Research target
ChEMBL	Activity	-	ACVRL1	-	Target : CHEMBL5311
ChEMBL	Activity	-	ALK	-	Target : CHEMBL4247
ChEMBL	Activity	-	AURKA	-	Target : CHEMBL4722
ChEMBL	Activity	-	AURKB	-	Target : CHEMBL2185
ChEMBL	Activity	-	AXL	-	Target : CHEMBL4895
ChEMBL	Activity	-	BLK	-	Target : CHEMBL2250
ChEMBL	Activity	-	BMP2K	-	Target : CHEMBL4522
ChEMBL	Activity	-	BRSK2	-	Target : CHEMBL4574
ChEMBL	Activity	-	BTK	-	Target : CHEMBL5251
ChEMBL	Activity	-	CDK16	-	Target : CHEMBL4597
ChEMBL	Activity	-	CLK1	-	Target : CHEMBL4224
ChEMBL	Activity	-	CLK2	-	Target : CHEMBL4225
ChEMBL	Activity	-	CLK4	-	Target : CHEMBL4203
ChEMBL	Activity	-	CSF1R	-	Target : CHEMBL1844
ChEMBL	Activity	-	CSK	-	Target : CHEMBL2634
ChEMBL	Activity	-	CSNK2A1	-	Target : CHEMBL3629
ChEMBL	Activity	-	CSNK2A2	-	Target : CHEMBL4070
ChEMBL	Activity	-	EIF2AK4	-	Target : CHEMBL5358
ChEMBL	Activity	-	EPHA3	-	Target : CHEMBL4954
ChEMBL	Activity	-	EPHA5	-	Target : CHEMBL3987
ChEMBL	Activity	-	EPHA6	-	Target : CHEMBL4526
ChEMBL	Activity	-	EPHA7	-	Target : CHEMBL4602
ChEMBL	Activity	-	EPHB1	-	Target : CHEMBL5072
ChEMBL	Activity	-	FER	-	Target : CHEMBL3982
ChEMBL	Activity	-	FES	-	Target : CHEMBL5455
ChEMBL	Activity	-	FGFR1	-	Target : CHEMBL3650
ChEMBL	Activity	-	FGFR3	-	Target : CHEMBL2742
ChEMBL	Activity	-	FGFR4	-	Target : CHEMBL3973
ChEMBL	Activity	-	FLT3	-	Target : CHEMBL1974
ChEMBL	Activity	-	FYN	-	Target : CHEMBL1841
ChEMBL	Activity	-	HCK	-	Target : CHEMBL3234
ChEMBL	Activity	-	IGF1R	-	Target : CHEMBL1957
ChEMBL	Activity	-	INSR	-	Target : CHEMBL1981
ChEMBL	Activity	-	INSRR	-	Target : CHEMBL5483
ChEMBL	Activity	-	KDR	-	Target : CHEMBL279
ChEMBL	Activity	-	LCK	-	Target : CHEMBL258
ChEMBL	Activity	-	LTK	-	Target : CHEMBL5627
ChEMBL	Activity	-	MAP4K5	-	Target : CHEMBL4852
ChEMBL	Activity	-	MAPK10	-	Target : CHEMBL2637
ChEMBL	Activity	-	MAPK8	-	Target : CHEMBL2276
ChEMBL	Activity	-	MARK1	-	Target : CHEMBL5940
ChEMBL	Activity	-	MARK4	-	Target : CHEMBL5754
ChEMBL	Activity	-	MERTK	-	Target : CHEMBL5331
ChEMBL	Activity	-	MUSK	-	Target : CHEMBL5684
ChEMBL	Activity	-	NEK2	-	Target : CHEMBL3835
ChEMBL	Activity	-	NTRK1	-	Target : CHEMBL2815
ChEMBL	Activity	-	NTRK2	-	Target : CHEMBL4898
ChEMBL	Activity	-	NTRK3	-	Target : CHEMBL5608
ChEMBL	Activity	-	PAK3	-	Target : CHEMBL2999
ChEMBL	Activity	-	PAK7	-	Target : CHEMBL4524
ChEMBL	Activity	-	PDGFRB	-	Target : CHEMBL1913
ChEMBL	Activity	-	PHKG2	-	Target : CHEMBL2349
ChEMBL	Activity	-	PLK4	-	Target : CHEMBL3788
ChEMBL	Activity	-	PRKAA1	-	Target : CHEMBL4045
ChEMBL	Activity	-	PRKAA2	-	Target : CHEMBL2116
ChEMBL	Activity	-	PTK2	-	Target : CHEMBL2695
ChEMBL	Activity	-	PTK2B	-	Target : CHEMBL5469
ChEMBL	Activity	-	RET	-	Target : CHEMBL2041
ChEMBL	Activity	-	ROS1	-	Target : CHEMBL5568
ChEMBL	Activity	-	RPS6KA1	-	Target : CHEMBL2553
ChEMBL	Activity	-	RPS6KA3	-	Target : CHEMBL2345
ChEMBL	Activity	-	RPS6KA4	-	Target : CHEMBL3125
ChEMBL	Activity	-	RPS6KA4	-	Target : CHEMBL3125
ChEMBL	Activity	-	RPS6KA5	-	Target : CHEMBL4237
ChEMBL	Activity	-	SLK	-	Target : CHEMBL4202
ChEMBL	Activity	-	SRC	-	Target : CHEMBL267
ChEMBL	Activity	-	SRPK1	-	Target : CHEMBL4375
ChEMBL	Activity	-	STK10	-	Target : CHEMBL3981
ChEMBL	Activity	-	STK16	-	Target : CHEMBL3938
ChEMBL	Activity	-	STK17A	-	Target : CHEMBL4525
ChEMBL	Activity	-	STK3	-	Target : CHEMBL4708
ChEMBL	Activity	-	STK33	-	Target : CHEMBL6005
ChEMBL	Activity	-	STK38L	-	Target : CHEMBL4851
ChEMBL	Activity	-	STK4	-	Target : CHEMBL4598
ChEMBL	Activity	-	TGFBR1	-	Target : CHEMBL4439
ChEMBL	Activity	-	TNIK	-	Target : CHEMBL4527
ChEMBL	Activity	-	TTK	-	Target : CHEMBL3983
ChEMBL	Activity	-	TXK	-	Target : CHEMBL4367
ChEMBL	Activity	-	TYK2	-	Target : CHEMBL3553
ChEMBL	Activity	-	ULK3	-	Target : CHEMBL5047
ChEMBL	Activity	-	YES1	-	Target : CHEMBL2073

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