Tan Lab | DSigDB

Gene Set: D4 : TTD - GW-8510

Collection

D4 : TTD

Chemical Name

GW-8510 ( From PubChem : GW8510 )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
449.505 g/mol	3	9	5.262	False(3/4)

Structure

InChI

InChI=1S/C21H15N5O3S2/c27-21-15(19-16(25-21)8-9-17-20(19)30-12-24-17)11-23-13-4-6-14(7-5-13)31(28,29)26-18-3-1-2-10-22-18/h1-12,23H,(H,22,26)(H,25,27)/b15-11-

InChIKey

GCYXEGSPUDSZJY-PTNGSMBKSA-N

Links

Gene (7 / 20)

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Source	Type	Unit	Value	Gene	PMID	Other
TTD	Inhibitor			CCNA2		Research target
TTD	Inhibitor			CDK2		Clinical trial target
TTD	Inhibitor			PCNA		Research target
PubChem	AC50_uM	uM	0.010	CDK5	-	GI(Protien) :
PubChem	AC50_uM	uM	0.016	CDK5	-	GI(Protien) :
PubChem	AC50_uM	uM	0.023	CDK5	-	GI(Protien) :
PubChem	AC50_uM	uM	0.418	CDK5	-	GI(Protien) :
PubChem	AC50_uM	uM	0.010	CDK5R1	-	GI(Protien) :
PubChem	AC50_uM	uM	0.016	CDK5R1	-	GI(Protien) :
PubChem	AC50_uM	uM	0.023	CDK5R1	-	GI(Protien) :
PubChem	AC50_uM	uM	0.418	CDK5R1	-	GI(Protien) :
PubChem	AC50_uM	uM	0.121	GSK3A	-	GI(Protien) :
PubChem	AC50_uM	uM	0.144	GSK3A	-	GI(Protien) :
PubChem	AC50_uM	uM	0.206	GSK3A	-	GI(Protien) :
PubChem	AC50_uM	uM	0.281	GSK3A	-	GI(Protien) :
PubChem	AC50_uM	uM	0.011	GSK3B	-	GI(Protien) :
PubChem	AC50_uM	uM	0.012	GSK3B	-	GI(Protien) :
PubChem	AC50_uM	uM	0.016	GSK3B	-	GI(Protien) :
PubChem	AC50_uM	uM	0.030	GSK3B	-	GI(Protien) :
PubChem	AC50_uM	uM	0.807	GSK3B	-	GI(Protien) :

Download gene sets

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