| Collection |
D4 : TTD |
| Chemical Name |
GSK-690693 ( From PubChem : G S K 6 9 0 6 9 3 ) |
| FDA |
NPC |
WHO |
Indian |
Australia |
China |
Traditional
Herbal |
Clinical
Trail |
| Not | Not | Not | Not | Not | Not | Not | Not |
|
Molecular
Weight |
Hydrogen Bond
Donor Count |
Hydrogen Bond
Acceptor Count |
cLogP |
Lipinski Rule |
| 425.484 g/mol |
3 |
10 |
2.4942 |
True |
|
| Structure |
|
| InChI |
I n C h I = 1 S / C 2 1 H 2 7 N 7 O 3 / c 1 - 4 - 2 8 - 1 8 - 1 5 ( 3 0 - 1 2 - 1 3 - 6 - 5 - 9 - 2 3 - 1 0 - 1 3 ) 1 1 - 2 4 - 1 4 ( 7 - 8 - 2 1 ( 2 , 3 ) 2 9 ) 1 6 ( 1 8 ) 2 5 - 2 0 ( 2 8 ) 1 7 - 1 9 ( 2 2 ) 2 7 - 3 1 - 2 6 - 1 7 / h 1 1 , 1 3 , 2 3 , 2 9 H , 4 - 6 , 9 - 1 0 , 1 2 H 2 , 1 - 3 H 3 , ( H 2 , 2 2 , 2 7 ) / t 1 3 - / m 0 / s 1 |
| InChIKey |
K G P G F Q W B C S Z G E L - Z D U S S C G K S A - N
|
| Links |
|
Gene
(11 /
15)
⊖ Less
|
| Source | Type | Unit | Value | Gene | PMID | Assay | Other | | TTD | Inhibitor | AKT1 | | | Clinical trial target | | TTD | Inhibitor | AKT1 | | | Clinical trial target | | TTD | Inhibitor | AKT2 | | | Clinical trial target | | TTD | Inhibitor | AKT2 | | | Clinical trial target | | TTD | Inhibitor | AKT3 | | | Clinical trial target | | TTD | Inhibitor | AKT3 | | | Clinical trial target | | TTD | Inhibitor | AKT3 | | | Research target | | TTD | Inhibitor | GSK3B | | | Clinical trial target | | TTD | Inhibitor | PRKCB | | | Clinical trial target | | TTD | Inhibitor | PRKCD | | | Research target | | TTD | Inhibitor | PRKCE | | | Research target | | TTD | Inhibitor | PRKCH | | | Research target | | TTD | Inhibitor | PRKCQ | | | Research target | | TTD | Inhibitor | ROCK1 | | | Clinical trial target | | PubChem | Potency | uM | 24.424 | YES1 |  | | GI(Protien) : |
|
| Download gene sets |
gmt, text, Detailed text
|
