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Gene Set: D4 : TTD - Gliquidone

Collection D4 : TTD
Chemical Name Gliquidone ( From PubChem : GLIQUIDONE )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotNotNotNotNotApprovedNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
527.632 g/mol 2 9 5.319 False(2/4)
Structure
InChI InChI=1S/C27H33N3O6S/c1-27(2)23-14-11-20(36-3)17-22(23)24(31)30(25(27)32)16-15-18-9-12-21(13-10-18)37(34,35)29-26(33)28-19-7-5-4-6-8-19/h9-14,17,19H,4-8,15-16H2,1-3H3,(H2,28,29,33)
InChIKey LLJFMFZYVVLQKT-UHFFFAOYSA-N
Links

Gene (9 / 13)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
TTDDrug(s)KCNJ10Successful target
PubChem PotencyuM10.000CYP3A4-GI(Protien) :
PubChem NoneuMCYP3A4-GI(Protien) :
PubChem Ratio Potency (uM)uM26.601NFE2L2-GI(Protien) :
PubChem Potency-Replicate_1uM26.601NR1H4-GI(Protien) :
PubChem Ratio Potency (uM)uM28.723NR1H4-GI(Protien) :
PubChem NoneuMPPARG-GI(Protien) :
ChEMBLActivity-ABCC8
-Target : CHEMBL2096972
ChEMBLAC50nM10000.000CYP3A4
-Target : CHEMBL340
ChEMBLPotencynM10000.000CYP3A4
-Target : CHEMBL340
ChEMBLPotencynM12589.300HSD17B10
-Target : CHEMBL4159
ChEMBLActivity-KCNJ11
-Target : CHEMBL2096972
ChEMBLPotencynM7943.300KDM4E
-Target : CHEMBL1293226
Download gene sets gmt, text, Detailed text
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