Tan Lab | DSigDB

Gene Set: D4 : TTD - Gemfibrozil

Collection

D4 : TTD

Chemical Name

Gemfibrozil ( From PubChem : GEMFIBROZIL )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Approved	Approved	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
250.333 g/mol	1	3	3.5732	True

Structure

InChI

InChI=1S/C15H22O3/c1-11-6-7-12(2)13(10-11)18-9-5-8-15(3,4)14(16)17/h6-7,10H,5,8-9H2,1-4H3,(H,16,17)

InChIKey

Links

Gene (15 / 21)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
TTD	Activator			LPL		Successful target
TTD	Drug(s)			LPL		Successful target
PubChem	Potency-Replicate_1	uM	48.904	AHR	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	6.310	CYP2C9	-	GI(Protien) :
PubChem	None	uM		CYP2C9	-	GI(Protien) :
PubChem	None	uM		NR1H2	-	GI(Protien) :
PubChem	None	uM		NR2F1	-	GI(Protien) :
PubChem	None	uM		NR5A1	-	GI(Protien) :
PubChem	None	uM		NR5A1	-	GI(Protien) :
PubChem	None	uM		NR5A2	-	GI(Protien) :
PubChem	None	uM		RARA	-	GI(Protien) :
PubChem	None	uM		RARA	-	GI(Protien) :
PubChem	None	uM		RARB	-	GI(Protien) :
PubChem	None	uM		RARG	-	GI(Protien) :
PubChem	None	uM		RORA	-	GI(Protien) :
PubChem	None	uM		RXRA	-	GI(Protien) :
ChEMBL	AC50	nM	6309.570	CYP2C9	-	Target : CHEMBL3397
ChEMBL	Potency	nM	6309.600	CYP2C9	-	Target : CHEMBL3397
ChEMBL	Activity	-		JUN	-	Target : CHEMBL4977
ChEMBL	Activity	-		PPARA	-	Target : CHEMBL239

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