Tan Lab | DSigDB

Gene Set: D4 : TTD - GALANGIN

Collection

D4 : TTD

Chemical Name

GALANGIN ( From PubChem : GALANGIN )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Approved	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
270.237 g/mol	3	5	2.5768	True

Structure

InChI

InChI=1S/C15H10O5/c16-9-6-10(17)12-11(7-9)20-15(14(19)13(12)18)8-4-2-1-3-5-8/h1-7,16-17,19H

InChIKey

Links

Gene (11 / 19)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
TTD	Inhibitor			ADORA2A		Successful target
TTD	Inhibitor			ADORA3		Successful target
TTD	Inhibitor			CYP1B1		Research target
PubChem	Potency	uM	12.990	ATAD5	-	GI(Protien) :
PubChem	IC50_CF-PAF_Mean	uM	3.270	CFTR	-	GI(Protien) :
PubChem	None	uM		CFTR	-	GI(Protien) :
PubChem	None	uM		CFTR	-	GI(Protien) :
PubChem	IC50_CF-PAF_Mean	uM		CFTR	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	3.981	CYP2C19	-	GI(Protien) :
PubChem	Potency	uM	3.162	CYP2C9	-	GI(Protien) :
PubChem	Potency	uM	19.953	CYP2D6	-	GI(Protien) :
PubChem	Potency	uM	15.849	CYP3A4	-	GI(Protien) :
PubChem	Potency	uM	29.855	TDP1	-	GI(Protien) :
ChEMBL	Potency	nM	12990.000	ATAD5	-	Target : CHEMBL1741209
ChEMBL	Potency	nM	3981.100	CYP2C19	-	Target : CHEMBL3622
ChEMBL	Potency	nM	3162.300	CYP2C9	-	Target : CHEMBL3397
ChEMBL	Potency	nM	19952.600	CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	15848.900	CYP3A4	-	Target : CHEMBL340

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