Tan Lab | DSigDB

Gene Set: D4 : TTD - FORMONONETIN

Collection

D4 : TTD

Chemical Name

FORMONONETIN ( From PubChem : FORMONONETIN )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Approved	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
268.264 g/mol	1	4	3.1742	True

Structure

InChI

InChI=1S/C16H12O4/c1-19-12-5-2-10(3-6-12)14-9-20-15-8-11(17)4-7-13(15)16(14)18/h2-9,17H,1H3

InChIKey

Links

Gene (11 / 17)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
TTD	Inhibitor			SLC5A2		Clinical trial target
PubChem	AhR Potency (uM)	uM	5.046	AHR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	6.859	AHR	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	1.536	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	5.495	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	7.761	ESR1	-	GI(Protien) :
PubChem	None	uM		MAPT	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	23.420	NFE2L2	-	GI(Protien) :
PubChem	None	uM		NR0B1	-	GI(Protien) :
PubChem	None	uM		NR0B1	-	GI(Protien) :
PubChem	None	uM		NR5A1	-	GI(Protien) :
PubChem	Potency	uM	11.220	SMN2	-	GI(Protien) :
ChEMBL	Potency	nM	39810.700	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	31622.800	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	39810.700	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	11220.200	SMN1; SMN2	-	Target : CHEMBL1293232

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