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Gene Set: D4 : TTD - Flutamide

Collection D4 : TTD
Chemical Name Flutamide ( From PubChem : FLUTAMIDE )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
ApprovedNotNotApprovedApprovedNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
276.212 g/mol 1 2 3.8043 True
Structure
InChI InChI=1S/C11H11F3N2O3/c1-6(2)10(17)15-7-3-4-9(16(18)19)8(5-7)11(12,13)14/h3-6H,1-2H3,(H,15,17)
InChIKey MKXKFYHWDHIYRV-UHFFFAOYSA-N
Links

Gene (13 / 39)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
TTDAntagonistARSuccessful target
TTDDrug(s)ARSuccessful target
PubChem NoneuMABCB1-GI(Protien) :
PubChem Potency-Replicate_1uM12.650AR-GI(Protien) :
PubChem Ratio Potency (uM)uM13.448AR-GI(Protien) :
PubChem AR Potency (uM)uM29.849AR-GI(Protien) :
PubChem Potency-Replicate_1uM29.849AR-GI(Protien) :
PubChem Potency-Replicate_1uM49.944AR-GI(Protien) :
PubChem Potency-Replicate_1uM61.131AR-GI(Protien) :
PubChem Potency-Replicate_1uM62.875CYP19A1-GI(Protien) :
PubChem NoneuMCYP19A1-GI(Protien) :
PubChem NoneuMCYP1A2-GI(Protien) :
PubChem NoneuMCYP1A2-GI(Protien) :
PubChem PotencyuM2.512EHMT2-GI(Protien) :
PubChem ER Potency (uM)uM27.644ESR1-GI(Protien) :
PubChem Potency-Replicate_1uM29.849ESR1-GI(Protien) :
PubChem Potency-Replicate_1uM48.966ESR1-GI(Protien) :
PubChem Potency-Replicate_1uM49.944ESR1-GI(Protien) :
PubChem Ratio Potency (uM)uM52.873ESR1-GI(Protien) :
PubChem ER Potency (uM)uM56.038ESR1-GI(Protien) :
PubChem NoneuMINS-GI(Protien) :
PubChem Potency-Replicate_1uM19.331NFE2L2-GI(Protien) :
PubChem Potency-Replicate_1uM23.708NFE2L2-GI(Protien) :
PubChem Ratio Potency (uM)uM26.601NFE2L2-GI(Protien) :
PubChem Ratio Potency (uM)uM35.721NFE2L2-GI(Protien) :
PubChem PotencyuM61.131NFE2L2-GI(Protien) :
PubChem PotencyuM66.824NFE2L2-GI(Protien) :
PubChem Potency-Replicate_1uM11.220NR1I2-GI(Protien) :
PubChem PotencyuM8.414TDP1-GI(Protien) :
PubChem PotencyuM9.200TDP1-GI(Protien) :
PubChem PotencyuM11.220TDP1-GI(Protien) :
PubChem PotencyuM11.582TDP1-GI(Protien) :
PubChem PotencyuM12.995TDP1-GI(Protien) :
PubChem PotencyuM13.336TDP1-GI(Protien) :
ChEMBLAC50nM316.230CYP1A2
-Target : CHEMBL3356
ChEMBLInhibition-CYP2C19
-Target : CHEMBL3622
ChEMBLInhibition-CYP2C9
-Target : CHEMBL3397
ChEMBLInhibition-CYP3A4
-Target : CHEMBL340
ChEMBLPotencynM2511.900EHMT2
-Target : CHEMBL6032
Download gene sets gmt, text, Detailed text
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