DSigDB

Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

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Gene Set: D4 : TTD - Fluocinolone Acetonide

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Collection	D4 : TTD
Chemical Name	Fluocinolone Acetonide ( From PubChem : FLUOCINOLONE ACETONIDE )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Approved Not Not Approved Not Approved Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 452.488 g/mol 2 6 2.3668 True
Structure
InChI	InChI=1S/C24H30F2O6/c1-20(2)31-19-9-13-14-8-16(25)15-7-12(28)5-6-21(15,3)23(14,26)17(29)10-22(13,4)24(19,32-20)18(30)11-27/h5-7,13-14,16-17,19,27,29H,8-11H2,1-4H3/t13-,14-,16-,17-,19+,21-,22-,23-,24+/m0/s1
InChIKey	FEBLZLNTKCEFIT-VSXGLTOVSA-N
Links
Gene (5 / 12) ⊖ Less	Source Type Unit Value Gene PMID Assay Other TTD Drug(s) SERPINA6 Successful target PubChem Potency-Replicate_1 uM 0.005 AR - GI(Protien) : PubChem Potency-Replicate_1 uM 21.872 AR - GI(Protien) : PubChem Ratio Potency (uM) uM 22.728 AR - GI(Protien) : PubChem Potency-Replicate_1 uM AR - GI(Protien) : PubChem None uM CFTR - GI(Protien) : PubChem None uM IL1B - GI(Protien) : PubChem Ratio Potency (uM) uM 0.001 NR3C1 - GI(Protien) : PubChem Potency-Replicate_1 uM 0.001 NR3C1 - GI(Protien) : PubChem Potency-Replicate_1 uM 0.004 NR3C1 - GI(Protien) : PubChem Ratio Potency (uM) uM 0.004 NR3C1 - GI(Protien) : PubChem None uM NR3C1 - GI(Protien) :
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