Gene Set: D4 : TTD - Bis-(5-hydroxy-1H-indol-2-yl)-methanone
| Collection |
D4 : TTD |
| Chemical Name |
Bis-(5-hydroxy-1H-indol-2-yl)-methanone ( From PubChem : F L T - 3 I N H I B I T O R I I ) |
| FDA |
NPC |
WHO |
Indian |
Australia |
China |
Traditional
Herbal |
Clinical
Trail |
| Not | Not | Not | Not | Not | Not | Not | Not |
|
Molecular
Weight |
Hydrogen Bond
Donor Count |
Hydrogen Bond
Acceptor Count |
cLogP |
Lipinski Rule |
| 292.289 g/mol |
4 |
3 |
3.2914 |
True |
|
| Structure |
|
| InChI |
I n C h I = 1 S / C 1 7 H 1 2 N 2 O 3 / c 2 0 - 1 1 - 1 - 3 - 1 3 - 9 ( 5 - 1 1 ) 7 - 1 5 ( 1 8 - 1 3 ) 1 7 ( 2 2 ) 1 6 - 8 - 1 0 - 6 - 1 2 ( 2 1 ) 2 - 4 - 1 4 ( 1 0 ) 1 9 - 1 6 / h 1 - 8 , 1 8 - 2 1 H |
| InChIKey |
N I M I W W Q L O G N Y H D - U H F F F A O Y S A - N
|
| Links |
|
Gene
(6 /
7)
⊖ Less
|
| Source | Type | Unit | Value | Gene | PMID | Assay | Other | | TTD | Inhibitor | ABL1 | | | Successful target | | TTD | Inhibitor | ABL2 | | | Successful target | | TTD | Inhibitor | FLT3 | | | Successful target | | TTD | Inhibitor | KIT | | | Successful target | | TTD | Inhibitor | PDGFRA | | | Discontinued target | | TTD | Inhibitor | PDGFRB | | | Research target | | ChEMBL | Activity | - | | FLT3
| - |  | Target : CHEMBL1974 |
|
| Download gene sets |
gmt, text, Detailed text
|
Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA
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