DSigDB Home
Search Gene
Collections
Browse Gene Sets
Download
Help

Gene Set: D4 : TTD - 3,7,3',4'-TETRAHYDROXYFLAVONE

Collection D4 : TTD
Chemical Name 3,7,3',4'-TETRAHYDROXYFLAVONE ( From PubChem : FISETIN )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotNotNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
286.236 g/mol 4 6 2.2824 True
Structure
InChI InChI=1S/C15H10O6/c16-8-2-3-9-12(6-8)21-15(14(20)13(9)19)7-1-4-10(17)11(18)5-7/h1-6,16-18,20H
InChIKey XHEFDIBZLJXQHF-UHFFFAOYSA-N
Links

Gene (21 / 35)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
TTDInhibitorCDK6Clinical trial target
TTDInhibitorCDK6Clinical trial target
TTDInhibitorFASNSuccessful target
PubChem PotencyuM15.849ALOX12-GI(Protien) :
PubChem PotencyuM1.995ALOX15-GI(Protien) :
PubChem PotencyuM5.012ALOX15-GI(Protien) :
PubChem NoneuMCSNK1G2-GI(Protien) :
PubChem NoneuMCYP1A2-GI(Protien) :
PubChem PotencyuM19.953CYP2C9-GI(Protien) :
PubChem PotencyuM39.811CYP3A4-GI(Protien) :
PubChem NoneuMMAP3K5-GI(Protien) :
PubChem PotencyuM12.589MAPK1-GI(Protien) :
PubChem PotencyuM5.012MAPT-GI(Protien) :
PubChem NoneuMPIM2-GI(Protien) :
PubChem PotencyuM0.398POLK-GI(Protien) :
PubChem PotencyuM0.562POLK-GI(Protien) :
PubChem NoneuMSTK16-GI(Protien) :
PubChem PotencyuM5.957TDP1-GI(Protien) :
PubChem PotencyuM6.684TDP1-GI(Protien) :
ChEMBLPotencynM15848.900ALOX12
-Target : CHEMBL3687
ChEMBLPotencynM1995.300ALOX15
-Target : CHEMBL2903
ChEMBLPotencynM5011.900ALOX15
-Target : CHEMBL2903
ChEMBLActivity-ALOX15
-Target : CHEMBL2903
ChEMBLPotencynM891.300APEX1
-Target : CHEMBL5619
ChEMBLPotencynM19952.600CYP2C9
-Target : CHEMBL3397
ChEMBLPotencynM39810.700CYP3A4
-Target : CHEMBL340
ChEMBLPotencynM31622.800HSD17B10
-Target : CHEMBL4159
ChEMBLPotencynM1258.900HSD17B10
-Target : CHEMBL4159
ChEMBLPotencynM2511.900HSD17B10
-Target : CHEMBL4159
ChEMBLPotencynM14125.400KDM4E
-Target : CHEMBL1293226
ChEMBLPotencynM12589.300MAPK1
-Target : CHEMBL4040
ChEMBLPotencynM5011.900MAPT
-Target : CHEMBL1293224
ChEMBLPotencynM3162.300RECQL
-Target : CHEMBL1293236
ChEMBLActivity-TOP1
-Target : CHEMBL1781
ChEMBLActivity-TOP2A
-Target : CHEMBL1806
Download gene sets gmt, text, Detailed text
Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

* Best viewed in the latest version of Chrome (42+), Safari (8+), IE (11+) or Firefox (35+).