Tan Lab | DSigDB

Gene Set: D4 : TTD - FAMOXADONE

Collection

D4 : TTD

Chemical Name

FAMOXADONE ( From PubChem : FAMOXADONE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
374.389 g/mol	1	6	4.7109	True

Structure

InChI

InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3/t22-/m0/s1

InChIKey

Links

Gene (9 / 16)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
TTD	Inhibitor			CYTB		Research target
PubChem	Potency-Replicate_1	uM	5.481	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	5.527	AR	-	GI(Protien) :
PubChem	AR Potency (uM)	uM	5.919	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	61.504	CYP19A1	-	GI(Protien) :
PubChem	Potency	uM	15.849	ESR1	-	GI(Protien) :
PubChem	ER Potency (uM)	uM	16.053	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	17.478	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	21.822	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	22.864	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.615	NFE2L2	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	1.013	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	35.481	NR1H4	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	24.688	PPARD	-	GI(Protien) :
PubChem	Potency	uM	31.623	RXRA	-	GI(Protien) :
ChEMBL	Activity	-		UQCR10	-	Target : CHEMBL2388

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